PLPP3 Antibodies

AND PLPP3 ELISA kits, PLPP3 Proteins

Many biological assays use antibodies to detect PLPP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PLPP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PLPP3 antibodies...

We validate the specificity of these antibodies to PLPP3 by testing them on tissues known to express PLPP3 positively and negatively. Browse below to find the PLPP3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLPP3 Infographic by Boster Bio

All PLPP3 Products

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Specificity

Applications

Price

Anti-PPAP2B PLPP3 Antibody

Western blot analysis of various lysates, using PPAP2B antibody at 1:1100 dilution

Human, Mouse, Rat

IHC, WB

$405
Cat # A12857
100ul

Anti-PPAP2B Antibody (N-term)

Human, Rat

$299
Cat # M12857
80 µl

Phosphatidic acid phosphatase type 2B (PLPP3) (NM_003713) Human Over-expression Lysate

Phosphatidic acid phosphatase type 2B (PLPP3) Human Over-expression Lysates NM_003713

Human

$628
Cat # LS008613
20 µg, 100 µg

PLPP3 Overview

Facts about Phospholipid phosphatase 3.

PLPP3 3D structure. Source: alphafold

Phospholipid phosphatase 3 (PLPP3)

Catalyzes the conversion of phosphatidic acid (PA) to diacylglycerol (DG). In addition it hydrolyzes lysophosphatidic acid (LPA), ceramide-1-phosphate (C-1-P) and sphingosine-1- phosphate (S-1-P).

The relative catalytic efficiency is LPA = PA > C-1-P > S-1-P. May be involved in cell adhesion and in cell-cell interactions.

Gene Information

Human
Gene Name:	PLPP3
Uniprot:	O14495
Entrez:	8613

Family

Belongs to:

PA-phosphatase related phosphoesterase family

Alternative Names

Phospholipid phosphatase 3

Molecular Weight

Mass (kDA):
35.116 kDA

Genomic Context


Human

Location:	1p32.2
Sequence:	1; NC_000001.11 (56494761..56579563, complement)

Tissue Specificity

Ubiquitously expressed. Highly expressed in heart and placenta.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Membrane raft; Multi-pass membrane protein. Cycles between the endoplasmic reticulum and the Golgi.

Interacting Proteins

CTNND1

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLPP3

References

PMID: 9305923 by Kai M., et al. Cloning and characterization of two human isozymes of Mg2+- independent phosphatidic acid phosphatase.

PMID: 9705349 by Roberts R., et al. Human type 2 phosphatidic acid phosphohydrolases. Substrate specificity of the type 2a, 2b, and 2c enzymes and cell surface activity of the 2a isoform.