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Pleiotropic regulator 1 Antibodies

AND PLRG1 ELISA kits, Pleiotropic regulator 1 Proteins

Many biological assays use antibodies to detect Pleiotropic regulator 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Pleiotropic regulator 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Pleiotropic regulator 1 antibodies...

We validate the specificity of these antibodies to Pleiotropic regulator 1 by testing them on tissues known to express PLRG1 positively and negatively. Browse below to find the PLRG1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLRG1 Infographic by Boster Bio

PLRG1 protein infographic

All PLRG1 Products

Product

Figures

Specificity

Applications

Price

PLRG1 (NM_002669) Human Over-expression Lysate

Human

$628
Cat # LS005356
100 µg

PLRG1 Overview

Facts about Pleiotropic regulator 1.

PLRG1 3D structure

PLRG1 3D structure. Source: alphafold

Pleiotropic regulator 1 (PLRG1)

Involved in pre-mRNA splicing as part of the spliceosome (PubMed:28502770, PubMed:28076346). Part of the PRP19-CDC5L complex that forms an essential component of the spliceosome and is necessary for activating pre-mRNA splicing (PubMed:11101529, PubMed:11544257).

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Gene Information

Human
Gene Name:	PLRG1
Uniprot:	O43660
Entrez:	5356

Gene Information

Family

Belongs to:

WD repeat PRL1/PRL2 family

Family

Alternative Names

MGC110980; pleiotropic regulator 1 (PRL1 homolog, Arabidopsis); PRL1Arabidopsis homolog)

Molecular Weight

Mass (kDA):
57.194 kDA

Molecular Weight

Genomic Context


Human

Location:	4q31.3
Sequence:	4; NC_000004.12 (154534997..154550433, complement)

Subcellular Localizations

Nucleus. Nucleus speckle.

Subcellular Localization

Diseases

Choledocholithiasis
Anemia
Werner Syndrome
Pancreatic Diseases
Cholecystolithiasis
Cholecystitis
Pancreatitis
Pancreatitis, Chronic
Ataxia Telangiectasia
Carcinoma, Pancreatic Ductal

Malignant Neoplasms
Neoplasms
Pancreatic Neoplasm
Shwachman Syndrome
Malignant Neoplasm Of Pancreas

Disease

Interacting Proteins

CDC5L
HNRNPM

Interacting Proteins

Pathways

Cell Division
Cell Cycle
Dna Repair
Methylation
Mismatch Repair
Mrna Splicing
Cell Proliferation
Cell Cycle Checkpoint
S Phase

Gallstone Formation
Tissue Homeostasis
Rna Splicing

Pathways

PTMs

Phosphorylation

Methylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLRG1

References

PMID: 9765207 by Nemeth K., et al. Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis.

PMID: 11101529 by Ajuh P., et al. Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry.