PMP22 Antibodies

AND PMP22 ELISA kits, PMP22 Proteins

Many biological assays use antibodies to detect PMP22, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PMP22 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PMP22 antibodies...

We validate the specificity of these antibodies to PMP22 by testing them on tissues known to express PMP22 positively and negatively. Browse below to find the PMP22 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for PMP22? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PMP22 Western Blot Guide

PMP22 Infographic by Boster Bio

All PMP22 Products

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Product

Figures

Specificity

Applications

Price

Anti-PMP22 Monoclonal Antibody

All lanes use the Antibody at 1:1K dilution for 1 hour at room temperature

Western blot analysis of PMP22 expression in 293T cell lysate

Human, Rat

$370
Cat # M00890
100 μl

PMP22 (NM_000304) Human Over-expression Lysate

PMP22 Human Over-expression Lysates NM_000304

Human

$628
Cat # LS005376
20 µg, 100 µg

PMP22 Colorimetric Cell-Based ELISA Kit

Western blot analysis of extracts from MDA-MB-435 cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1478
1 kit, containing one 96-well plate and all necessary reagents

PMP22 (NM_153322) Human Recombinant Protein

Coomassie blue staining of purified PMP22 protein

$1249
Cat # PROTQ01453
20 µg

PMP22 Overview

Facts about Peripheral myelin protein 22.

PMP22 3D structure. Source: alphafold

Peripheral myelin protein 22 (PMP22)

Might be involved in growth regulation, and in myelinization in the peripheral nervous system. .

Gene Information

Human
Gene Name:	PMP22
Uniprot:	Q01453
Entrez:	5376

Family

Belongs to:

PMP-22/EMP/MP20 family

Alternative Names

CMT1A; CMT1E; GAS3; GAS-3DSS; growth arrest-specific 3; Growth arrest-specific protein 3; HMSNIA; HNPP; MGC20769; peripheral myelin protein 22; PMP-22; Sp110

Molecular Weight

Mass (kDA):
17.891 kDA

Genomic Context


Human

Location:	17p12
Sequence:	17; NC_000017.11 (15229777..15265326, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Charcot-marie-tooth Disease
Inherited Neuropathy
Peripheral Neuropathy
Hereditary Motor And Sensory Neuropathies
Hereditary Liability To Pressure Palsies
Charcot-marie-tooth Disease, Type Ia (disorder)
Nervousness
Demyelination
Polyneuropathy
Demyelinating Diseases
Dejerine-sottas Disease (disorder)
Weakness

Atrophy
Sensory Neuropathy
Muscular Atrophy
Neoplasms
Tissue Adhesions
Demyelinating Polyneuropathy
Muscle Weakness

Interacting Proteins

KLRC1
SMIM3

Pathways

Myelination
Pathogenesis
Cell Proliferation
Localization
Regeneration
Cell Death
Cell Growth
Schwann Cell Proliferation
Muscle Atrophy
Transport
Cell Differentiation
Meiosis
Cell Adhesion

Translation
Aging
Cell Cycle
Glycosylation
Schwann Cell Differentiation
Programmed Cell Death
Nerve Development

PTMs

Glycosylation
Phosphorylation
Cleavage
Ubiquitination
Methylation

Amination
Dephosphorylation
Ribosylation
Palmitoylation
Deglycosylation

Research Areas

Cellular Markers
Glia Markers
Membrane Trafficking and Chaperones
Neuroscience
Oligodendrocyte Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PMP22

References

PMID: 1303228 by Patel P.I., et al. The gene for the peripheral myelin protein PMP-22 is a candidate for Charcot-Marie-Tooth disease type 1A.

PMID: 1497668 by Hayasaka K., et al. Isolation and sequence determination of cDNA encoding PMP-22 (PAS- II/SR13/Gas-3) of human peripheral myelin.