PMPCA Antibodies

AND PMPCA ELISA kits, PMPCA Proteins

Many biological assays use antibodies to detect PMPCA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PMPCA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PMPCA antibodies...

We validate the specificity of these antibodies to PMPCA by testing them on tissues known to express PMPCA positively and negatively. Browse below to find the PMPCA antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for PMPCA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PMPCA Western Blot Guide

PMPCA Infographic by Boster Bio

All PMPCA Products

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Product

Figures

Specificity

Applications

Price

Anti-PMPCA/INPP5 Antibody Picoband®

Western blot analysis of PMPCA/INPP5 using anti-PMPCA/INPP5 antibody (A09623-1)

IHC analysis of PMPCA/INPP5 using anti-PMPCA/INPP5 antibody (A09623-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A09623-1
100 μg/vial

PMPCA (NM_015160) Human Over-expression Lysate

Human

$960
Cat # LS023203
20 µg, 100 µg

PMPCA (NM_015160) Human Recombinant Protein

Coomassie blue staining of purified PMPCA protein

$1062
Cat # PROTQ10713
20 µg

PMPCA Overview

Facts about Mitochondrial-processing peptidase subunit alpha.

PMPCA 3D structure. Source: alphafold

Mitochondrial-processing peptidase subunit alpha (PMPCA)

Substrate binding and recognition subunit of the essential mitochondrial processing protease (MPP), which is necessary for maturation of the majority of mitochondrial precursor proteins (PubMed:25808372). Many MPP cleavage sites follow an arginine at position -2 (By similarity).

Gene Information

Human
Gene Name:	PMPCA
Uniprot:	Q10713
Entrez:	23203

Family

Belongs to:

peptidase M16 family

Alternative Names

Alpha-MPPMGC104197; EC 3.4.24.64; inositol polyphosphate-5-phosphatase, 72 kD; INPP5E; KIAA0123FLJ26258; mitochondrial matrix processing protease, alpha subunit; mitochondrial-processing peptidase subunit alpha; MPPA; P-55; peptidase (mitochondrial processing) alpha

Molecular Weight

Mass (kDA):
58.253 kDA

Genomic Context


Human

Location:	9q34.3
Sequence:	9; NC_000009.12 (136410573..136423761)

Tissue Specificity

Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis.

Subcellular Localizations

Mitochondrion matrix. Mitochondrion inner membrane.

PTMs

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PMPCA

References

PMID: 11840567 by Harris R.A., et al. Cluster analysis of an extensive human breast cancer cell line protein expression map database.

PMID: 25808372 by Jobling R.K., et al. PMPCA mutations cause abnormal mitochondrial protein processing in patients with non-progressive cerebellar ataxia.