POLRMT Antibodies

AND POLRMT ELISA kits, POLRMT Proteins

Many biological assays use antibodies to detect POLRMT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with POLRMT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop POLRMT antibodies...

We validate the specificity of these antibodies to POLRMT by testing them on tissues known to express POLRMT positively and negatively. Browse below to find the POLRMT antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for POLRMT? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the POLRMT Western Blot Guide

POLRMT Infographic by Boster Bio

All POLRMT Products

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Product

Figures

Specificity

Applications

Price

Anti-POLRMT Antibody

Western blot analysis of extracts of various cell lines, using POLRMT antibody

Immunoprecipitation analysis of 200ug extracts of HepG2 cells, using 3 ug POLRMT antibody

Human

IF, WB

$405
Cat # A06341
100ul

mtRNA polymerase (POLRMT) (NM_005035) Human Over-expression Lysate

Human

$628
Cat # LS005442
20 µg, 100 µg

POLRMT Overview

Facts about DNA-directed RNA polymerase, mitochondrial.

POLRMT 3D structure. Source: alphafold

DNA-directed RNA polymerase, mitochondrial (POLRMT)

DNA-dependent RNA polymerase catalyzes the transcription of mitochondrial DNA into RNA using the four ribonucleoside triphosphates as substrates. .

Gene Information

Human
Gene Name:	POLRMT
Uniprot:	O00411
Entrez:	5442

Family

Belongs to:

phage and mitochondrial RNA polymerase family

Alternative Names

APOLMTEC 2.7.7.6; DNA-directed RNA polymerase, mitochondrial; h-mtRPOL; MTRNAP; MTRPOL; polymerase (RNA) mitochondrial (DNA directed)

Molecular Weight

Mass (kDA):
138.62 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (617221..633557, complement)

Subcellular Localizations

Mitochondrion.

Diseases

Hepatitis
Malignant Neoplasm Of Breast
Hepatitis C
Premature Aging Syndrome
Mitochondrial Damage
Cockayne Syndrome
Malignant Neoplasms
Neoplasms
Dwarfism

Cachexia
Sensorineural Hearing Loss (disorder)
Chimera Disorder
Peste Des Petits Ruminants Infection

Interacting Proteins

MRPL12

Pathways

Translation
Oxidative Phosphorylation
Dna Replication
Ribosome Biogenesis
Mitochondrial Translation
Single-stranded Dna Binding
Rna Interference
Aging
Cellular Process
Metaphase
Localization
Embryo Development

Mitochondrial Dna Replication
Blastocyst Formation
Methylation
Cell Cycle
Protein Import
Autophagy

PTMs

Phosphorylation

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/POLRMT

References

PMID: 9097968 by Tiranti V., et al. Identification of the gene encoding the human mitochondrial RNA polymerase (h-mtRPOL) by cyberscreening of the Expressed Sequence Tags database.

PMID: 12068295 by Falkenberg M., et al. Mitochondrial transcription factors B1 and B2 activate transcription of human mtDNA.