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Ppp2r2d Antibodies
AND Ppp2r2d ELISA kits, Ppp2r2d Proteins
Many biological assays use antibodies to detect Ppp2r2d, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ppp2r2d in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ppp2r2d antibodies...
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Ppp2r2d Overview
Facts about Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform.
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform (Ppp2r2d)
B regulatory subunit of protein phosphatase 2A (PP2A) that plays an integral role in cell cycle by controlling mitosis entrance and exit. The activity of PP2A complexes comprising PPP2R2D (PR55- delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis.
During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment (By similarity).
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Ppp2r2d |
| Uniprot: | Q925E7 |
| Entrez: | 52432 |
Family
| Belongs to: |
|---|
| phosphatase 2A regulatory subunit B family |
Alternative Names
KIAA1541; MDS026; PP2A subunit B isoform B55-delta; PP2A subunit B isoform delta; PP2A subunit B isoform PR55-delta; PP2A subunit B isoform R2-delta; protein phosphatase 2, regulatory subunit B, delta isoform; protein phosphatase 2, regulatory subunit B, delta; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B deltaisoform
Molecular Weight
Mass (kDA):
51.957 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 7 F4|7 82.95 cM |
| Sequence: | 7; |
Diseases
- Malignant Neoplasms
- Neoplasms
- Neurofibromatosis 1
- Dysequilibrium Syndrome
- Carcinoma
Pathways
- Cellular Localization
- Mitosis
- Dna Repair
- Cell Growth
- Exit From Mitosis
- Regulation Of Cell Growth
PTMs
- Dephosphorylation
Research Areas
- Protein Phosphatase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ppp2r2d
bosterbio.com/bosterbio-gene-info-cards/Ppp2r2d
References
PMID: 14621295 by Okazaki N., et al. Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
PMID: 21183079 by Huttlin E.L., et al. A tissue-specific atlas of mouse protein phosphorylation and expression.