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PRKAG2 Antibodies
AND PRKAG2 ELISA kits, PRKAG2 Proteins
Many biological assays use antibodies to detect PRKAG2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKAG2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKAG2 antibodies...
Designing a Western blot for PRKAG2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PRKAG2 Western Blot GuidePRKAG2 Infographic by Boster Bio
All PRKAG2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02758-3
100 μg/vial
Cat # A02758-3
100 μg/vial
PRKAG2 Overview
Facts about 5'-AMP-activated protein kinase subunit gamma-2.
5'-AMP-activated protein kinase subunit gamma-2 (PRKAG2)
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation.
AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin.
Gene Information
| Human | |
|---|---|
| Gene Name: | PRKAG2 |
| Uniprot: | Q9UGJ0 |
| Entrez: | 51422 |
Family
| Belongs to: |
|---|
| 5'-AMP-activated protein kinase gamma subunit family |
Alternative Names
AAKG; AAKG2; CMH6AMPK subunit gamma-2; H91620pAMPK gamma2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; WPWS5'-AMP-activated protein kinase subunit gamma-2
Molecular Weight
Mass (kDA):
63.066 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q36.1 |
| Sequence: | 7; NC_000007.14 (151556114..151877115, complement) |
Tissue Specificity
Isoform B is ubiquitously expressed except in liver and thymus. The highest level is detected in heart with abundant expression in placenta and testis.
Diseases
- Hypertrophy
- Cardiomyopathies
- Hypertrophic Cardiomyopathy
- Wolff-parkinson-white Syndrome
- Cardiac Hypertrophy
- Left Ventricular Hypertrophy
- Glycogen Storage Disease
- Cardiac Arrhythmia
- Pre-excitation Syndromes
- Danon Disease
- Heart Diseases
- Cardiomyopathy, Hypertrophic, Familial
Pathways
- Pathogenesis
- Energy Homeostasis
- Cardiac Conduction
- Transport
- Glomerular Filtration
- Fatty Acid Oxidation
- Glycolysis
- Aging
- Response To Metformin
- Localization
PTMs
Research Areas
- Lipid and Metabolism
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRKAG2
bosterbio.com/bosterbio-gene-info-cards/PRKAG2
References
PMID: 10698692 by Cheung P.C.F., et al. Characterization of AMP-activated protein kinase gamma-subunit isoforms and their role in AMP binding.
PMID: 11112354 by Lang T.M., et al. Molecular cloning, genomic organization, and mapping of PRKAG2, a heart abundant gamma-2 subunit of 5'-AMP-activated protein kinase, to human chromosome 7q36.