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- Table of Contents
PRKAR2A Antibodies
AND PRKAR2A ELISA kits, PRKAR2A Proteins
Many biological assays use antibodies to detect PRKAR2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRKAR2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRKAR2A antibodies...
Designing a Western blot for PRKAR2A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PRKAR2A Western Blot GuidePRKAR2A Infographic by Boster Bio
All PRKAR2A Products
Product
Figures
Specificity
Applications
Price
Anti-PKA R2/PKR2/PRKAR2A Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03911-2
100 μg/vial
Cat # A03911-2
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # P03911
100 μl
Cat # P03911
100 μl
PRKAR2A Overview
Facts about cAMP-dependent protein kinase type II-alpha regulatory subunit.
cAMP-dependent protein kinase type II-alpha regulatory subunit (PRKAR2A)
Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PRKAR2A |
| Uniprot: | P13861 |
| Entrez: | 5576 |
Family
| Belongs to: |
|---|
| cAMP-dependent kinase regulatory chain family |
Alternative Names
protein kinase, cAMP-dependent, regulatory, type II, alpha; RII-alpha subunit
Molecular Weight
Mass (kDA):
45.518 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (48744601..48847874, complement) |
Tissue Specificity
Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
Subcellular Localizations
Cytoplasm. Cell membrane. Colocalizes with PJA2 in the cytoplasm and the cell membrane.
Diseases
- Neoplasms
- Malignant Neoplasms
- Leukemia
- Carcinogenesis
- Neoplasms, Experimental
- Carcinoma
- Myeloid Leukemia
- Salivary Gland Diseases
- Malignant Paraganglionic Neoplasm
- Precursor B-cell Lymphoblastic Leukemia-lymphoma
- Endometrial Polyp
- Leukemia, Myelocytic, Acute
Interacting Proteins
- AKAP1
- AKAP3
- AKAP5
- AKAP8
Pathways
- Localization
- Mitosis
- Cell Activation
- Cell Differentiation
- Interphase
- Cell Cycle
- T Cell Activation
- Spermatogenesis
- Cell Proliferation
- Transcytosis
- Meiosis
- Decidualization
- Secretion
PTMs
- Phosphorylation
- Reduction
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRKAR2A
bosterbio.com/bosterbio-gene-info-cards/PRKAR2A
References
PMID: 2540040 by Oyen O., et al. Human testis cDNA for the regulatory subunit RII alpha of cAMP- dependent protein kinase encodes an alternate amino-terminal region.
PMID: 9003463 by Foss K.B., et al. Molecular cloning, upstream sequence and promoter studies of the human gene for the regulatory subunit RII alpha of cAMP-dependent protein kinase.
1 Publications of Boster PRKAR2A Antibodies & ELISA Kits
- PubMed ID: 10.1016/j.prostaglandins.2021.106595, Epoxyeicosatrienoic Acids Prevent Cardiomyocytes against Sepsis by A2AR-induced ...
*More publications can be found for each product on its corresponding product page