PRMT2 Antibodies

AND PRMT2 ELISA kits, PRMT2 Proteins

Many biological assays use antibodies to detect PRMT2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRMT2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRMT2 antibodies...

We validate the specificity of these antibodies to PRMT2 by testing them on tissues known to express PRMT2 positively and negatively. Browse below to find the PRMT2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRMT2 Infographic by Boster Bio

All PRMT2 Products

Product

Figures

Specificity

Applications

Price

Anti-PRMT2 Antibody

Human, Mouse, Rat

IF, IHC, WB

$405
Cat # A04706
100ul

PRMT2 (NM_206962) Human Recombinant Protein

$1249
Cat # PROTP55345
20 µg

Anti-PRMT2 Mouse Monoclonal Antibody [Clone ID: OTI3A3]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M04706
100 µl

PRMT2 (NM_206962) Human Over-expression Lysate

Human

$628
Cat # LS003275
100 µg

PRMT2 Overview

Facts about Protein arginine N-methyltransferase 2.

PRMT2 3D structure. Source: alphafold

Protein arginine N-methyltransferase 2 (PRMT2)

Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation.

Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Improves PGR, PPARG, RARA-mediated transactivation.

Gene Information

Human
Gene Name:	PRMT2
Uniprot:	P55345
Entrez:	3275

Family

Belongs to:

class I-like SAM-binding methyltransferase superfamily

Alternative Names

EC 2.1.1.-; EC 2.1.1.125; Histone-arginine N-methyltransferase PRMT2; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1; HMT1 hnRNP methyltransferase-like 1 (S. cerevisiae); HMT1 hnRNP methyltransferase-like 1; HMT1; HRMT1L1PRMT2 beta; MGC111373; PRMT2 alpha; PRMT2 gamma; protein arginine methyltransferase 2; protein arginine N-methyltransferase 2

Molecular Weight

Mass (kDA):
49.042 kDA

Genomic Context


Human

Location:	21q22.3
Sequence:	21; NC_000021.9 (46635156..46665685)

Tissue Specificity

Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord.

Subcellular Localizations

[Isoform 1]: Cytoplasm. Nucleus. Translocates from the cytoplasm to the nucleus, after hormone exposure. Excluded from nucleolus.; [Isoform PRMT2Alpha]: Nucleus. Excluded from nucleolus.; [Isoform PRMT2Beta]: Cytoplasm. Nucleus. Nucleus, nucleolus.; [Isoform PRMT2Gamma]: Nucleus. Excluded from nucleolus.; [Isoform PRMT2L2]: Cytoplasm. Nucleus. Predominantly cytoplasmic.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Neoplasms
Mammary Neoplasms
Down Syndrome
Inflammation
Carcinoma
Chromosomal Deletion
Inflammatory Response
Pneumonia
Learning Disorders
Epithelial Metaplasia

Mastitis-metritis-agalactia Syndrome
Hypoxia
Aneuploidy
Dyslexia
Ulcer
Cytomegalovirus Infections
Lymphoma

Interacting Proteins

CBLB
ESR1
HTT
RB1
RBM12

Pathways

Methylation
Localization
Histone Methylation
Dna Methylation
Protein Methylation
Transport
Nuclear Export
Cell Cycle
Cytokinesis
Virulence
Inflammatory Response
Mrna Processing
Rna Splicing

Cell Growth
Rna Processing
Secretion
Response To Pheromone
Cell Activation
Colony Morphology
Histone Modification

PTMs

Methylation
Acetylation

Phosphorylation
Cleavage

Acylation

Research Areas

Apoptosis
Chromatin Research

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRMT2

References

PMID: 9545638 by Scott H.S., et al. Identification and characterization of two putative human arginine methyltransferases (HRMT1L1 and HRMT1L2).

PMID: 9196002 by Katsanis N., et al. Identification and mapping of a novel human gene, HRMT1L1, homologous to the rat protein arginine N-methyltransferase 1 (PRMT1) gene.