Prion-like protein doppel Antibodies

AND PRND ELISA kits, Prion-like protein doppel Proteins

Many biological assays use antibodies to detect Prion-like protein doppel, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prion-like protein doppel in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prion-like protein doppel antibodies...

We validate the specificity of these antibodies to Prion-like protein doppel by testing them on tissues known to express PRND positively and negatively. Browse below to find the PRND antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRND Infographic by Boster Bio

All PRND Products

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Product

Figures

Specificity

Applications

Price

Human PRND Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ9UKY0
Starting from 4ug

Anti-Human PRND Antibody

Human

$470
Cat # DZ41695
200 μl/vial

Anti-PRND Antibody Picoband®

Western blot analysis of PRND using anti-PRND antibody (A05457-1)

IHC analysis of PRND using anti-PRND antibody (A05457-1)

IF analysis of PRND using anti-PRND antibody (A05457-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05457-1
100 μg/vial

PRND Overview

Facts about Prion-like protein doppel.

PRND 3D structure. Source: alphafold

Prion-like protein doppel (PRND)

Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu(2+) (PubMed:15218028, PubMed:20411530).

Gene Information

Human
Gene Name:	PRND
Uniprot:	Q9UKY0
Entrez:	23627

Family

Belongs to:

prion family

Alternative Names

Prion-like protein doppel

Molecular Weight

Mass (kDA):
20.293 kDA

Genomic Context


Human

Location:	20p13
Sequence:	20; NC_000020.11 (4721909..4728460)

Tissue Specificity

Expressed in testis, in Sertoli cells, ejaculated spermatozoa and in seminal fluid (at protein level).

Subcellular Localizations

Cell membrane; Lipid-anchor, GPI-anchor.

PTMs

Disulfide bond
Glycoprotein

GPI-anchor
Lipoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRND

References

PMID: 10525406 by Moore R.C., et al. Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel.

PMID: 11063595 by Lu K., et al. Expression and structural characterization of the recombinant human doppel protein.