PRPS1 Antibodies

AND PRPS1 ELISA kits, PRPS1 Proteins

Many biological assays use antibodies to detect PRPS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PRPS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PRPS1 antibodies...

We validate the specificity of these antibodies to PRPS1 by testing them on tissues known to express PRPS1 positively and negatively. Browse below to find the PRPS1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PRPS1 Infographic by Boster Bio

All PRPS1 Products

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Product

Figures

Specificity

Applications

Price

Anti-PRPS1 Antibody

Western blot analysis of extracts of various cell lines, using PRPS1 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A02704
100ul

PRPS1 (NM_002764) Human Recombinant Protein

Coomassie blue staining of purified PRPS1 protein

$1249
Cat # PROTP60891
20 µg

PRPS1 (NM_002764) Human Over-expression Lysate

Human

$628
Cat # LS005631
20 µg, 100 µg

Anti-PRPS1 Antibody

Human, Mouse, Rat

ELISA, IP, IF, IHC, ICC, WB

$370
Cat # A02704-1
100 μl/vial

PRPS1 Overview

Facts about Ribose-phosphate pyrophosphokinase 1.

PRPS1 3D structure. Source: alphafold

Ribose-phosphate pyrophosphokinase 1 (PRPS1)

Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) which is vital for nucleotide synthesis. .

Gene Information

Human
Gene Name:	PRPS1
Uniprot:	P60891
Entrez:	5631

Family

Belongs to:

ribose-phosphate pyrophosphokinase family

Alternative Names

CMTX5ARTS; deafness, X-linked 2, perceptive, congenital; DFN2; DFNX1KIAA0967; dJ1070B1.2 (phosphoribosyl pyrophosphate synthetase 1); EC 2.7.6.1; Phosphoribosyl pyrophosphate synthase I; phosphoribosyl pyrophosphate synthetase 1; PPRibP; PRSI; PRS-I; ribose-phosphate diphosphokinase 1; ribose-phosphate pyrophosphokinase 1

Molecular Weight

Mass (kDA):
34.834 kDA

Genomic Context


Human

Location:	Xq22.3
Sequence:	X; NC_000023.11 (107628424..107651026)

Diseases

Gout
Genetic Diseases, X-linked
Hyperuricemia
Sensorineural Hearing Loss (disorder)
Ataxia, Fatal X-linked, With Deafness And Loss Of Vision
Ataxia
Complete Hearing Loss
Lesch-nyhan Syndrome
Muscle Hypotonia
Optic Atrophy
Sarcoma

Atrophy
Peripheral Neuropathy
Purine Metabolism Disorder
Optic Atrophies, Hereditary
Mitochondrial Diseases
Confusion

Interacting Proteins

GORASP2
PRPS2
PRPSAP1
PRPSAP2
SPG21

Pathways

Metaphase
Localization
Chromosome Localization
Reverse Transcription
Translation
Cell Cycle
Meiotic Cell Cycle
Oocyte Maturation
Pathogenesis

Rna Interference
Dosage Compensation
Meiosis

Research Areas

Apoptosis
Core ESC-Like Genes
Lipid and Metabolism
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PRPS1

References

PMID: 2155397 by Roessler B.J., et al. Cloning of two distinct copies of human phosphoribosylpyrophosphate synthetase cDNA.

PMID: 1650777 by Sonoda T., et al. Complete nucleotide sequence of human phosphoribosyl pyrophosphate synthetase subunit I (PRS I) cDNA and a comparison with human and rat PRPS gene families.