PSME2 Antibodies

AND PSME2 ELISA kits, PSME2 Proteins

Many biological assays use antibodies to detect PSME2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PSME2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PSME2 antibodies...

We validate the specificity of these antibodies to PSME2 by testing them on tissues known to express PSME2 positively and negatively. Browse below to find the PSME2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PSME2 Infographic by Boster Bio

All PSME2 Products

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Product

Figures

Specificity

Applications

Price

Anti-PSME2 Antibody

Western blot (WB) analysis of PSME2 polyclonal antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A07053
100ul

Anti-PSME2 Antibody Picoband®

Western blot analysis of PSME2 using anti-PSME2 antibody (A07053-1)

IHC analysis of PSME2 using anti-PSME2 antibody (A07053-1)

IF analysis of PSME2 using anti-PSME2 antibody (A07053-1)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07053-1
100 μg/vial

PSME2 (NM_002818) Human Recombinant Protein

Coomassie blue staining of purified PSME2 protein

$1249
Cat # PROTQ9UL46
20 µg

PSME2 (NM_002818) Human Over-expression Lysate

Human

$628
Cat # LS005721
20 µg, 100 µg

PSME2 Overview

Facts about Proteasome activator complex subunit 2.

PSME2 3D structure. Source: alphafold

Proteasome activator complex subunit 2 (PSME2)

Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.

Gene Information

Human
Gene Name:	PSME2
Uniprot:	Q9UL46
Entrez:	5721

Family

Belongs to:

PA28 family

Alternative Names

11S regulator complex beta subunit; 11S regulator complex subunit beta; Activator of multicatalytic protease subunit 2; MCP Activator; MCP activator, 31-kD subunit; PA28 Activator beta Subunit; PA28b; PA28betacell migration-inducing protein 22; proteasome (prosome, macropain) activator subunit 2 (PA28 beta); Proteasome activator 28 subunit beta; proteasome activator 28-beta; proteasome activator complex subunit 2; proteasome activator hPA28 subunit beta; PSME2; REGbeta; REG-beta

Molecular Weight

Mass (kDA):
27.402 kDA

Genomic Context


Human

Location:	14q12
Sequence:	14; NC_000014.9 (24143365..24146646, complement)

Diseases

Cytomegalovirus Infections
Neoplasms
Malignant Neoplasms
Carcinoma
Muscular Atrophy
Leukemia
Stomach Neoplasms
Neoplasm Metastasis
Melanoma
Ataxia
Gastric Adenocarcinoma
Influenza

Adenocarcinoma
Inflammation
Neurodegenerative Disorders
Cardiomyopathies
Toxoplasmosis
Sclerosis

Interacting Proteins

PSME1

Pathways

Proteolysis
Immune Response
Cell Cycle
Pathogenesis
Transport
Reverse Transcription
Proteasome Assembly
Cell Proliferation
Dna Replication
Aging
Tumor Necrosis Factor Production
Oxidative Phosphorylation
Cell Division

Translation
Mrna Processing
Cell-cell Signaling
Atp-dependent Proteolysis
Protein Oxidation
Intracellular Signal Transduction
Response To Interferon-gamma

PTMs

Phosphorylation
Ubiquitination

Cleavage
Oxidation

Research Areas

Neuroscience
Ubiquitin Proteasome Pathway

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PSME2

References

PMID: 10199920 by McCusker D., et al. Organization of the genes encoding the human proteasome activators PA28alpha and beta.

PMID: 7789512 by Ahn J.Y., et al. Primary structures of two homologous subunits of PA28, a gamma- interferon-inducible protein activator of the 20S proteasome.