Tyrosine-protein phosphatase non-receptor type 14 (PTPN14)

Protein tyrosine phosphatase which may play a role in the regulation of lymphangiogenesis, cell-cell adhesion, cell- matrix adhesion, cell migration, cell growth and also regulates TGF-beta gene expression, thereby modulating epithelial- mesenchymal transition. Mediates beta-catenin dephosphorylation at adhesion junctions.

Acts as a negative regulator of the oncogenic property of YAP, a downstream target of the hippo pathway, in a mobile density-dependent method. May function as a tumor suppressor.