PTPN3 Antibodies

AND PTPN3 ELISA kits, PTPN3 Proteins

Many biological assays use antibodies to detect PTPN3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPN3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPN3 antibodies...

We validate the specificity of these antibodies to PTPN3 by testing them on tissues known to express PTPN3 positively and negatively. Browse below to find the PTPN3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTPN3 Infographic by Boster Bio

All PTPN3 Products

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Anti-PTPN3 Antibody

Western blot analysis of extracts of various cell lines, using PTPN3 antibody at 1:1000 dilution

Human, Mouse, Rat

$405
Cat # A06227
100ul

PTPH1 (PTPN3) (NM_002829) Human Over-expression Lysate

Human

$960
Cat # LS005774
20 µg, 100 µg

PTPN3 Overview

Facts about Tyrosine-protein phosphatase non-receptor type 3.

PTPN3 3D structure. Source: alphafold

Tyrosine-protein phosphatase non-receptor type 3 (PTPN3)

May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.

Gene Information

Human
Gene Name:	PTPN3
Uniprot:	P26045
Entrez:	5774

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

DKFZp686N0569; EC 3.1.3.48; protein tyrosin phosphatase H1; protein tyrosine phosphatase, non-receptor type 3; Protein-tyrosine phosphatase H1; PTP-H1; PTPH1cytoskeletal-associated protein tyrosine phosphatase; tyrosine phosphatase; tyrosine-protein phosphatase non-receptor type 3

Molecular Weight

Mass (kDA):
103.99 kDA

Genomic Context


Human

Location:	9q31.3
Sequence:	9; NC_000009.12 (109375694..109538395, complement)

Subcellular Localizations

Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.

Diseases

Malignant Neoplasms
Posttransfusion Purpura
Neoplasms
Colorectal Cancer
Carcinoma
Cell Transformation, Neoplastic
Malignant Tumor Of Colon
Liver Carcinoma
Malignant Paraganglionic Neoplasm
Colorectal Neoplasms
Liver Neoplasms
Colonic Neoplasms
Carcinogenesis

Cytogenetic Abnormality
Lymphatic Metastasis
Malignant Neoplasm Of Stomach
Stomach Neoplasms
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Hepatitis B

Interacting Proteins

AKR1C1
GHR
LMO1
MCC
NXT2

SCN5A
SDHA
VANGL1
VANGL2
VCP

VDR
WDR6
YWHAB
YWHAG
YWHAZ

ZCCHC10

Pathways

Cell Proliferation
Localization
Cell Growth
Cell Activation
T Cell Activation
Oncogenesis
Secretion
Cell-cell Signaling
Cell Development
Cytokine Secretion
Sensitization

T Cell Differentiation
Cytokine Production
Sperm Motility
Cell Cycle
Cell Death
Cell Differentiation

PTMs

Phosphorylation

Dephosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPN3

References

PMID: 1648725 by Yang Q., et al. Isolation of a cDNA clone encoding a human protein-tyrosine phosphatase with homology to the cytoskeletal-associated proteins band 4.1, ezrin, and talin.

PMID: 1626183 by Arimura Y., et al. cDNA cloning of new protein tyrosine phosphatases in the human colon.