PTPRF Antibodies

AND PTPRF ELISA kits, PTPRF Proteins

Many biological assays use antibodies to detect PTPRF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPRF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPRF antibodies...

We validate the specificity of these antibodies to PTPRF by testing them on tissues known to express PTPRF positively and negatively. Browse below to find the PTPRF antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for PTPRF? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PTPRF Western Blot Guide

PTPRF Infographic by Boster Bio

All PTPRF Products

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Applications

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Anti-LAR/PTPRF Antibody Picoband®

IHC analysis of LAR using anti-LAR antibody (PB9786)

Western blot analysis of LAR using anti-LAR antibody (PB9786)

Human

IHC, WB

$370
Cat # PB9786
100 μg/vial

Anti-Liprin-alpha-3 PPFIA3 Antibody

Western blot analysis of PPFIA3 in 293 cell lysate with PPFIA3 antibody at (A) 1 and (B) 2 μg/ml

Human, Mouse, Rat

ELISA, WB

$481
Cat # A11239
0.1 mg

PTPRF Overview

Facts about Receptor-type tyrosine-protein phosphatase F.

PTPRF 3D structure. Source: alphafold

Receptor-type tyrosine-protein phosphatase F (PTPRF)

Potential cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.

Gene Information

Human
Gene Name:	PTPRF
Uniprot:	P10586
Entrez:	5792

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

LAR; LCA-homolog; protein tyrosine phosphatase, receptor type, F; PTPRF; receptor type, F polypeptide; receptor-linked protein-tyrosine phosphatase LAR; receptor-type tyrosine-protein phosphatase F

Molecular Weight

Mass (kDA):
212.879 kDA

Genomic Context


Human

Location:	1p34.2
Sequence:	1; NC_000001.11 (43522238..43623672)

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Posttransfusion Purpura
Neoplasms
Malignant Neoplasms
Tissue Adhesions
Nervousness
Neoplasm Metastasis
Cell Transformation, Neoplastic
Disease Of Adrenal Medulla
Malignant Neoplasm Of Breast
Carcinoma
Diabetes Mellitus
Tumor Angiogenesis
Pheochromocytoma

Adenocarcinoma
Congenital Abnormality
Liver Carcinoma
Adrenal Gland Neoplasms
Prostatic Neoplasms
Tumor Progression
Malignant Neoplasm Of Lung

Pathways

Cell Adhesion
Localization
Regeneration
Cell Proliferation
Cell Growth
Cell Migration
Cell Motility
Axon Guidance
Pathogenesis
Transport
Hyperphosphorylation
Neurogenesis
Mammary Gland Development

System Development
Contact Inhibition
Gland Development
Cell Development
Methylation
Cell Death
Nervous System Development

PTMs

Phosphorylation
Dephosphorylation

Cleavage
Methylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPRF

References

PMID: 2972792 by Streuli M., et al. A new member of the immunoglobulin superfamily that has a cytoplasmic region homologous to the leukocyte common antigen.

PMID: 15491607 by Homma K., et al. Alternative splice variants encoding unstable protein domains exist in the human brain.