PTPRT Antibodies

AND PTPRT ELISA kits, PTPRT Proteins

Many biological assays use antibodies to detect PTPRT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTPRT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTPRT antibodies...

We validate the specificity of these antibodies to PTPRT by testing them on tissues known to express PTPRT positively and negatively. Browse below to find the PTPRT antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PTPRT Infographic by Boster Bio

All PTPRT Products

Product

Figures

Specificity

Applications

Price

Anti-PTPRT Antibody

Human, Mouse

ELISA, WB

$380
Cat # A05344
100ul

PTP rho (PTPRT) (NM_133170) Human Over-expression Lysate

Human

$960
Cat # LS011122
100 µg

PTPRT Overview

Facts about Receptor-type tyrosine-protein phosphatase T.

PTPRT 3D structure. Source: alphafold

Receptor-type tyrosine-protein phosphatase T (PTPRT)

May be involved in both signal transduction and cellular adhesion in the CNS. .

Gene Information

Human
Gene Name:	PTPRT
Uniprot:	O14522
Entrez:	11122

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

EC 3.1.3; EC 3.1.3.48; KIAA0283RPTPrho; protein tyrosine phosphatase, receptor type, T; PTP rho; PTPRT; receptor protein tyrosine phosphatase; Receptor-type tyrosine-protein phosphatase rho; receptor-type tyrosine-protein phosphatase T; RPTP-rho; R-PTP-T

Molecular Weight

Mass (kDA):
162.134 kDA

Genomic Context


Human

Location:	20q12-q13.11
Sequence:	20; NC_000020.11 (42029959..43189906, complement)

Tissue Specificity

Expressed in colon, lung, heart and testis, as well as in fetal and adult brain. Not detected in muscle and peripheral blood leukocytes.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Tissue Adhesions
Nervousness
Malignant Tumor Of Colon
Colorectal Cancer
Cell Transformation, Neoplastic
Colorectal Neoplasms
Posttransfusion Purpura
Neoplasm Metastasis
Malignant Neoplasm Of Breast
Colonic Neoplasms
Neoplasms, Experimental

Cardiac Hypertrophy
Sleep Disorders
Malignant Neoplasm Of Lung
Carcinoma
Neoplasms, Hormone-dependent
Somnambulism
Mammary Neoplasms

Interacting Proteins

GRB2
Nlgn1
Nlgn2
Nrxn1
Nrxn3

PTPRN

Pathways

Cell Adhesion
Localization
Cell-cell Adhesion
Reverse Transcription
Cell Migration
Cell Proliferation
Regulation Of Signal Transduction

Pathogenesis
Homophilic Cell Adhesion

PTMs

Phosphorylation

Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTPRT

References

PMID: 9602027 by McAndrew P.E., et al. Identification and characterization of RPTP rho, a novel RPTP mu/kappa-like receptor protein tyrosine phosphatase whose expression is restricted to the central nervous system.

PMID: 9179496 by Ohara O., et al. Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins.