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- Table of Contents
Facts about 6-pyruvoyl tetrahydrobiopterin synthase.
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Human | |
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Gene Name: | PTS |
Uniprot: | Q03393 |
Entrez: | 5805 |
Belongs to: |
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PTPS family |
6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; EC 4.2.3.12; FLJ97081; PTPSPTP synthase
Mass (kDA):
16.386 kDA
Human | |
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Location: | 11q23.1 |
Sequence: | 11; NC_000011.10 (112226428..112233973) |
Boster Bio is a great resource for finding the right antibodies to help you in your research. There are many benefits of their antibodies, including their high affinity and specificity. Here are just few of the many benefits. You can read more about them here. This article also discusses the CXCL8 IL6 antibody. These are the four most important antibodies to use in research.
The ENTPD1 protein hydrolyzes extracellular purine TP (TPNTP), a poisonous compound for human cells. The ENTPD1 genome is associated with IL-6 and many other interleukin-signaling genes. The ENTPD1 protein is also associated to the TCR repertoire. This suggests that it may play a role in modulating signaling pathways. The ENTPD1 marker has been shown to be highly expressed in tumor-infiltrating lymphocytes and cytotoxic memory T cells.
The ENTPD1 enzyme, which is involved in purinergic nervetransmission, is found in many tissues throughout our bodies. The ENTPD1 drug detects the activity of the enzyme. The ENTPD1 indicator is a potential drug to treat vascular disorders. However, it could not be safe to humans. It also depends on its utility in research.
There is a strong correlation between ENTPD1 gene expression and POC1A gene expression in GC. This suggests that the POC1A protein affects immune regulation. It also influences the outcome for GC patients. One of the most useful uses of the PTS marker is the ENTPD1 antibody. It binds POC1A (a protein found within GC).
Boster Biological Technology, Wuhan, China's IL6 antibody is an important tool in prognostic research as well as patient care. It is a very useful marker for predicting outcome in patients with different cancer types. IL-6, a biomarker that detects cancer in saliva, is also useful. Doctors can detect cancer by using IL-6 in saliva to detect the stage.
IL-6 is produced in a variety of tissues and organs, including the skin, lungs, and gut. It is produced by our immune system and has many cellular targets. IL-6 and its relatives play many roles in the immune system. They regulate cancer cell growth and proliferation. Research into the cytokine's regulators may be critical to the development of new treatments and biomarkers for the disease.
IL-6 is a crucial cytokine in acute phase response. It plays a key part in the pathogenesis and progression of many types of cancer. It is a powerful indicator in a variety liquids, including serum as well as bronchoalveolar levage fluid. It can also react to various types of chemopreventive drug, small molecules, and monoclonal antibodies.
Inflammation and infection are common conditions associated with the overexpression of IL-8. Its anti-inflammatory qualities are due to its ability to chemoattract many cell types, including neutrophils. IL-8 is a key mediator to the NFkB pathway and is expressed by a broad spectrum of normal cells as well as tumor cells.
Cells expressing toll-like receptors, or TLRs, produce IL-8. It is a signatory chemokine for CR2-positive naive T cells. Macrophages are the first cells in the body to produce IL-8. IL-8 can be released in a variety forms, including the monomer or homodimer forms. These are more potent. However, homodimer activity is inhibited by methylation of Leu25.
Although this cytokine is not currently a clinically-available treatment for cancer, it has shown promise in clinical trials. Its roles in cancer biology are evident through its protein localization and gene expression. More research is needed to determine whether this is a useful cytokine in the treatment. This treatment has the potential of revolutionizing cancer treatments. This breakthrough is part of an ongoing research program by Boster Bio.
Although IL-17, IL-8 and IL-17 are well-known angiogenic inducers, their role in the treatment of cancer remains unclear. CRL4, which encodes the cytokine receptor IL17RB (also known as CRL4), binds IL17B/IL17E. It could also play a role in the development of hematopoietic cell.
PMID: 1282802 by Thoeny B., et al. Human 6-pyruvoyltetrahydropterin synthase: cDNA cloning and heterologous expression of the recombinant enzyme.
PMID: 8216273 by Ashida A., et al. cDNA cloning, expression in Escherichia coli and purification of human 6-pyruvoyl-tetrahydropterin synthase.