PTS Antibodies

AND PTS ELISA kits, PTS Proteins

Many biological assays use antibodies to detect PTS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTS antibodies...

We validate the specificity of these antibodies to PTS by testing them on tissues known to express PTS positively and negatively. Browse below to find the PTS antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for PTS? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the PTS Western Blot Guide

PTS Infographic by Boster Bio

All PTS Products

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Product

Figures

Specificity

Applications

Price

Anti-Phospho-PTS (S19) Rabbit Monoclonal Antibody

Western blot analysis of Phospho-PTS (S19) expression in (1) HUVEC cell lysate; (2) HUVEC cell treated with Alkaline Phosphatase lysate

Human

IF, IHC, ICC, WB

$370
Cat # P00430
100 μl/vial

PTS (NM_000317) Human Over-expression Lysate

Human

$628
Cat # LS005805
20 µg, 100 µg

PTS (NM_000317) Human Recombinant Protein

Coomassie blue staining of purified PTS protein

$1249
Cat # PROTQ03393
20 µg

PTS Overview

Facts about 6-pyruvoyl tetrahydrobiopterin synthase.

PTS 3D structure. Source: alphafold

6-pyruvoyl tetrahydrobiopterin synthase (PTS)

Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6- pyruvoyl tetrahydropterin.

Gene Information

Human
Gene Name:	PTS
Uniprot:	Q03393
Entrez:	5805

Family

Belongs to:

PTPS family

Alternative Names

6-pyruvoyl tetrahydrobiopterin synthase; 6-pyruvoyltetrahydropterin synthase; EC 4.2.3.12; FLJ97081; PTPSPTP synthase

Molecular Weight

Mass (kDA):
16.386 kDA

Genomic Context


Human

Location:	11q23.1
Sequence:	11; NC_000011.10 (112226428..112233973)

Diseases

Thrombosis
Deep Vein Thrombosis
Venous Thrombosis
Noise-induced Hearing Loss
Postthrombotic Syndrome
Post-traumatic Stress Disorder
Malignant Neoplasms
Neoplasms
Pain
Salmonella Infections
Myocardial Infarction
Infarction
Multiple Trauma

Edema
Pulmonary Embolism
Postphlebitic Syndrome
Hemorrhage
Hypertensive Disease
Embolism
Depressive Disorder

Interacting Proteins

COIL
LNX1
SDCBP
THAP10

Pathways

Transport
Glucose Transport
Fermentation
Virulence
Localization
Glycolysis
Chemotaxis
Carbohydrate Transport
Protein Import
Cell Death
Lactose Transport
Pathogenesis
Polyamine Transport

Coagulation
Biofilm Formation
Protein Phosphorylation
Translation
Excretion
Cell Growth
Phosphoenolpyruvate-dependent Sugar Phosphotransferase System

PTMs

Phosphorylation
Dephosphorylation
Oxidation
Cleavage
Glycosylation
Hydroxylation
Ubiquitination
Reduction

Methylation
Carboxylation
Decarboxylation
Acylation
Ribosylation
Iodination
Nitration
Deacetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTS

References

PMID: 1282802 by Thoeny B., et al. Human 6-pyruvoyltetrahydropterin synthase: cDNA cloning and heterologous expression of the recombinant enzyme.

PMID: 8216273 by Ashida A., et al. cDNA cloning, expression in Escherichia coli and purification of human 6-pyruvoyl-tetrahydropterin synthase.