PURA Antibodies

AND PURA ELISA kits, PURA Proteins

Many biological assays use antibodies to detect PURA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PURA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PURA antibodies...

We validate the specificity of these antibodies to PURA by testing them on tissues known to express PURA positively and negatively. Browse below to find the PURA antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PURA Infographic by Boster Bio

All PURA Products

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Price

PURA (NM_005859) Human Over-expression Lysate

Human

$628
Cat # LS005813
20 µg, 100 µg

Anti-PURA Antibody Picoband®

Western blot analysis of PURA using anti-PURA antibody (A02520-1)

IHC analysis of PURA using anti-PURA antibody (A02520-1)

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # A02520-1
100 μg/vial

PURA Overview

Facts about Transcriptional activator protein Pur-alpha.

PURA 3D structure. Source: alphafold

Transcriptional activator protein Pur-alpha (PURA)

This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination.

Gene Information

Human
Gene Name:	PURA
Uniprot:	Q00577
Entrez:	5813

Family

Belongs to:

PUR DNA-binding protein family

Alternative Names

PUR1PUR-ALPHA; PURALPHA; purine-rich element binding protein A; Purine-rich single-stranded DNA-binding protein alpha; transcriptional activator protein Pur-alpha

Molecular Weight

Mass (kDA):
34.911 kDA

Genomic Context


Human

Location:	5q31.3
Sequence:	5; NC_000005.10 (140114109..140125619)

Subcellular Localizations

Nucleus.

Diseases

Salmonella Infections
Malignant Neoplasms
Immunologic Deficiency Syndromes
Hiv Infections
Prostatic Neoplasms
Nervousness
Neoplasms
Myeloid Leukemia
Acquired Immunodeficiency Syndrome
Leukoencephalopathies
Malignant Neoplasm Of Prostate
Leukemia

Cell Transformation, Neoplastic
Leukoencephalopathy, Progressive Multifocal
Escherichia Coli Infections
Tissue Adhesions
Retinoblastoma
Horse Diseases
Glioblastoma

Interacting Proteins

Pathways

Dna Replication
Cell Growth
Transport
Translation
Cell Cycle
Virulence
Single-stranded Dna Binding
Cell Proliferation
Localization
Brain Development
Dna Repair
Rna Transport
S Phase

Pathogenesis
Immune Response
Cell Cycle Arrest
Mitosis
Myelination
Cell Differentiation
Regeneration

PTMs

Phosphorylation
Glycosylation
Carboxylation

Deamination
Acetylation
Dephosphorylation

Methylation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PURA

References

PMID: 1448097 by Bergemann A.D., et al. Sequence of cDNA comprising the human pur gene and sequence-specific single-stranded-DNA-binding properties of the encoded protein.

PMID: 25439098 by Lalani S.R., et al. Mutations in PURA cause profound neonatal hypotonia, seizures, and encephalopathy in 5q31.3 microdeletion syndrome.