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- Table of Contents
Facts about Pygopus homolog 1.
Human | |
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Gene Name: | PYGO1 |
Uniprot: | Q9Y3Y4 |
Entrez: | 26108 |
Belongs to: |
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No superfamily |
DKFZp547G0910; Pygo1; pygopus 1; pygopus homolog 1 (Drosophila); pygopus homolog 1; Pygopus1; Pygopus-1; pygopus-like protein 1
Mass (kDA):
45.116 kDA
Human | |
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Location: | 15q21.3 |
Sequence: | 15; NC_000015.10 (55538884..55588971, complement) |
Nucleus.
PMID: 11955446 by Kramps T., et al. Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex.
PMID: 17113272 by Hoffmans R., et al. BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling.