Plexin-A2 Antibodies

AND PLXNA2 ELISA kits, Plexin-A2 Proteins

Many biological assays use antibodies to detect Plexin-A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Plexin-A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Plexin-A2 antibodies...

We validate the specificity of these antibodies to Plexin-A2 by testing them on tissues known to express PLXNA2 positively and negatively. Browse below to find the PLXNA2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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PLXNA2 Infographic by Boster Bio

All PLXNA2 Products

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Anti-Plexin-A2 PLXNA2 Antibody

Western blot (WB) analysis of PLXNA2 polyclonal antibody at 1:500 dilution
Lane1:A549 whole cell lysate
Lane2:Raw264

Human, Mouse, Rat

$405
Cat # A05706
100ul

Plexin A2 (PLXNA2) (NM_025179) Human Over-expression Lysate

Human

$960
Cat # LS005362
20 µg, 100 µg

PLXNA2 Overview

Facts about Plexin-A2.

PLXNA2 3D structure. Source: alphafold

Plexin-A2 (PLXNA2)

Coreceptor for SEMA3A and SEMA6A.
Necessary for indicating by SEMA6A and class 3 semaphorins and subsequent remodeling of the cytoskeleton.

Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin.

Gene Information

Human
Gene Name:	PLXNA2
Uniprot:	O75051
Entrez:	5362

Family

Belongs to:

plexin family

Alternative Names

FLJ11751; FLJ30634; KIAA0463plexin 2; OCT; OCTSemaphorin receptor OCT; Plexin A2; PLXN2; PLXN2plexin-A2; PLXNA2; transmembrane protein OCT

Molecular Weight

Mass (kDA):
211.104 kDA

Genomic Context


Human

Location:	1q32.2
Sequence:	1; NC_000001.11 (208022242..208244384, complement)

Tissue Specificity

Detected in fetal brain.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein.

Diseases

Nervousness
Schizophrenia
Crest Syndrome
Malignant Neoplasms
Neoplasms
Heart Diseases
Congenital Heart Defects
Malignant Neoplasm Of Breast
Tumor Angiogenesis
Mammary Neoplasms
Osteoporosis
Mental Disorders
Tumor Progression

Congenital Heart Disease
Nerve Damage
Neoplasm Metastasis
Double Outlet Right Ventricle
Atresia
Peripheral Nerve Injuries
Personality Disorders

Interacting Proteins

Pathways

Axon Guidance
Cell Migration
Induction Of Apoptosis
Regeneration
Angiogenesis
Neural Tube Closure
Transposition
Somal Translocation
Osteoblast Differentiation
Neurogenesis
Ossification
Cartilage Development
Axon Extension

Chemotaxis
System Development
Segmentation
Endochondral Ossification
Cell-cell Signaling
Cell Proliferation
Nerve Development

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PLXNA2

References

PMID: 8570614 by Maestrini E., et al. A family of transmembrane proteins with homology to the MET- hepatocyte growth factor receptor.

PMID: 10520995 by Tamagnone L., et al. Plexins are a large family of receptors for transmembrane, secreted and GPI-anchored semaphorins in vertebrates.