RAB3GAP1 Antibodies

AND RAB3GAP1 ELISA kits, RAB3GAP1 Proteins

Many biological assays use antibodies to detect RAB3GAP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAB3GAP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAB3GAP1 antibodies...

We validate the specificity of these antibodies to RAB3GAP1 by testing them on tissues known to express RAB3GAP1 positively and negatively. Browse below to find the RAB3GAP1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for RAB3GAP1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the RAB3GAP1 IHC Guide

RAB3GAP1 Infographic by Boster Bio

All RAB3GAP1 Products

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Specificity

Applications

Price

Anti-RAB3GAP1 Antibody Picoband®

Western blot analysis of RAB3GAP1 using anti-RAB3GAP1 antibody (A04789-2)

IHC analysis of RAB3GAP1 using anti-RAB3GAP1 antibody (A04789-2)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A04789-2
100 µg/vial

Anti-Zebrafish RAB3GAP1 Antibody Picoband®

Western blot analysis of RAB3GAP1 using anti-RAB3GAP1 antibody (AZQ6NUV0)

IHC analysis of RAB3GAP1 using anti-RAB3GAP1 antibody (AZQ6NUV0)

Zebrafish

IHC, WB

$470
Cat # AZQ6NUV0
100 μg/vial

RAB3GAP1 (NM_001172435) Human Over-expression Lysate

Human

$960
Cat # LS022930
20 µg, 100 µg

RAB3GAP1 Overview

Facts about Rab3 GTPase-activating protein catalytic subunit.

RAB3GAP1 3D structure. Source: alphafold

Rab3 GTPase-activating protein catalytic subunit (RAB3GAP1)

Probable catalytic subunit of a GTPase activating protein which has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones.

Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development.

Gene Information

Human
Gene Name:	RAB3GAP1
Uniprot:	Q15042
Entrez:	22930

Family

Belongs to:

Rab3-GAP catalytic subunit family

Alternative Names

KIAA0066P130; RAB3 GTPase activating protein subunit 1 (catalytic); RAB3 GTPase-activating protein 130 kDa subunit; rab3 GTPase-activating protein catalytic subunit; Rab3-GAP p130; Rab3-GAP; RAB3GAPDKFZp434A012; WARBM1RAB3GAP130

Molecular Weight

Mass (kDA):
110.524 kDA

Genomic Context


Human

Location:	2q21.3
Sequence:	2; NC_000002.12 (135052281..135176667)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. In neurons, it is enriched in the synaptic soluble fraction.

Diseases

Microcephaly
Hypogonadism
Warburg Sjo Fledelius Syndrome
Corneal Diseases
Optic Atrophy
Microphthalmos
Hypoplasia
Polymicrogyria
Dysplasia
Cortical Dysplasia
Atrophy

Cataract
Nervousness
Mild Mental Retardation
Agenesis Of Corpus Callosum
Sclerosis
Primary Lateral Sclerosis

Pathways

Exocytosis
Transport
System Development
Nervous System Development
Pathogenesis
Eye Development
Localization

Myelination
Cholesterol Homeostasis

PTMs

Ribosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAB3GAP1

References

PMID: 9030515 by Fukui K., et al. Isolation and characterization of a GTPase activating protein specific for the Rab3 subfamily of small G proteins.

PMID: 9852129 by Oishi H., et al. Localization of the Rab3 small G protein regulators in nerve terminals and their involvement in Ca2+-dependent exocytosis.