RAB3GAP2 Antibodies

AND RAB3GAP2 ELISA kits, RAB3GAP2 Proteins

Many biological assays use antibodies to detect RAB3GAP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAB3GAP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAB3GAP2 antibodies...

We validate the specificity of these antibodies to RAB3GAP2 by testing them on tissues known to express RAB3GAP2 positively and negatively. Browse below to find the RAB3GAP2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for RAB3GAP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the RAB3GAP2 Western Blot Guide

RAB3GAP2 Infographic by Boster Bio

All RAB3GAP2 Products

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Specificity

Applications

Price

Anti-RAB3GAP2 Antibody Picoband®

IHC analysis of RAB3GAP2 using anti-RAB3GAP2 antibody (A07244-3)

Human, Mouse, Rat

ELISA, IHC, WB

$370
Cat # A07244-3
100 μg/vial

Anti-PPP1R13B Antibody Picoband®

Western blot analysis of PPP1R13B using anti-PPP1R13B antibody (A07257-2)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A07257-2
100 µg/vial

RAB3GAP2 (NM_012414) Human Over-expression Lysate

Human

$960
Cat # LS025782
20 µg, 100 µg

RAB3GAP2 Overview

Facts about Rab3 GTPase-activating protein non-catalytic subunit.

RAB3GAP2 3D structure. Source: alphafold

Rab3 GTPase-activating protein non-catalytic subunit (RAB3GAP2)

Regulatory subunit of a GTPase activating protein which has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones.

Rab3 GTPase-activating complex especially converts active Rab3-GTP into the inactive form Rab3- GDP. Required for normal eye and brain development.

Gene Information

Human
Gene Name:	RAB3GAP2
Uniprot:	Q9H2M9
Entrez:	25782

Family

Belongs to:

Rab3-GAP regulatory subunit family

Alternative Names

DKFZP434D245; FLJ14579; KIAA0839p150; RAB3 GTPase activating protein subunit 2 (non-catalytic); Rab3 GTPase-activating protein 150 kDa subunit; rab3 GTPase-activating protein non-catalytic subunit; Rab3-GAP p150; Rab3-GAP regulatory subunit; RAB3GAP150; RAB3-GAP150; RGAP-iso

Molecular Weight

Mass (kDA):
155.985 kDA

Genomic Context


Human

Location:	1q41
Sequence:	1; NC_000001.11 (220148293..220272453, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Cytoplasm. In neurons, it is enriched in the synaptic soluble fraction.

Diseases

Hypogonadism
Warburg Sjo Fledelius Syndrome
Optic Atrophy
Microcephaly
Corneal Diseases
Microphthalmos
Cataract
Mild Mental Retardation
Nerve Degeneration
Developmental Delay (disorder)
Atrophy

Muscle Hypotonia
Hypoplasia
Polymicrogyria
Nervousness
Agenesis Of Corpus Callosum

Pathways

Exocytosis
Eye Development
Pathogenesis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAB3GAP2

References

PMID: 9733780 by Nagano F., et al. Molecular cloning and characterization of the noncatalytic subunit of the Rab3 subfamily-specific GTPase-activating protein.

PMID: 22337587 by Haines D.S., et al. Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.