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- Table of Contents
RAB6A Antibodies
AND RAB6A ELISA kits, RAB6A Proteins
Many biological assays use antibodies to detect RAB6A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RAB6A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RAB6A antibodies...
Designing a Western blot for RAB6A? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RAB6A Western Blot GuideRAB6A Infographic by Boster Bio
All RAB6A Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02912-2
100 μg/vial
Cat # A02912-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A02913-1
100 µg/vial
Cat # A02913-1
100 µg/vial
RAB6A Overview
Facts about Ras-related protein Rab-6A.
Ras-related protein Rab-6A (RAB6A)
Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER).
Has a very low GTPase activity. Involved in COPI-independent retrograde transport from the Golgi to the ER (PubMed:25962623).
Gene Information
| Human | |
|---|---|
| Gene Name: | RAB6A |
| Uniprot: | P20340 |
| Entrez: | 5870 |
Family
| Belongs to: |
|---|
| small GTPase superfamily |
Alternative Names
GTP-binding protein RAB6A'; GTP-binding protein RAB6B; Oncogene RAB6; Rab GTPase; Rab-6; RAB6, member RAS oncogene family; Rab6A variant 3; RAB6A'; RAB6A, member RAS oncogene family; RAB6B; RAB6rab-6; ras-related protein Rab-6A
Molecular Weight
Mass (kDA):
23.593 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.4 |
| Sequence: | 11; NC_000011.10 (73675638..73761074, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Golgi apparatus membrane; Lipid-anchor. BICD2 facilitates its targeting to Golgi apparatus membrane.; [Isoform 1]: Golgi apparatus membrane; Lipid-anchor.; [Isoform 2]: Golgi apparatus membrane; Lipid-anchor.
Diseases
- Neuroblastoma
- Hypopigmentation-immunodeficiency Disease
- Lymphohistiocytosis, Hemophagocytic
- Legionnaires' Disease
- Prion Diseases
- Adenocarcinoma
- Cell Transformation, Neoplastic
- Melanoma
- Neurodegenerative Disorders
- Endometrial Adenocarcinoma
- Endometrial Neoplasms
- Oculocerebrorenal Syndrome
Interacting Proteins
- Dennd5a
- GCC2
- OCRL
- PMM1
Pathways
- Transport
- Intracellular Transport
- Mitosis
- Metaphase
- Endocytosis
- Cell Cycle
- Cell Differentiation
- Cell Growth
- Secretion
- Sulfation
- Secretory Pathway
- Response To Stress
- Glycosylation
PTMs
- Glycosylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RAB6A
bosterbio.com/bosterbio-gene-info-cards/RAB6A
References
PMID: 2501306 by Zahraoui A., et al. The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.
PMID: 10996854 by Caillol N., et al. Impairment of bile salt-dependent lipase secretion in human pancreatic tumoral SOJ-6 cells.