RABGGTB Antibodies

AND RABGGTB ELISA kits, RABGGTB Proteins

Many biological assays use antibodies to detect RABGGTB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RABGGTB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RABGGTB antibodies...

We validate the specificity of these antibodies to RABGGTB by testing them on tissues known to express RABGGTB positively and negatively. Browse below to find the RABGGTB antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RABGGTB Infographic by Boster Bio

All RABGGTB Products

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Product

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Specificity

Applications

Price

Anti-RABGGTB Antibody

Western blot analysis of extracts of various cell lines, using RABGGTB antibody at 1:1000 dilution

Human, Mouse, Rat

IHC, WB

$405
Cat # A10765
100ul

RABGGTB (NM_004582) Human Over-expression Lysate

Human

$628
Cat # LS005876
20 µg, 100 µg

RABGGTB Overview

Facts about Geranylgeranyl transferase type-2 subunit beta.

RABGGTB 3D structure. Source: alphafold

Geranylgeranyl transferase type-2 subunit beta (RABGGTB)

Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A. .

Gene Information

Human
Gene Name:	RABGGTB
Uniprot:	P53611
Entrez:	5876

Family

Belongs to:

protein prenyltransferase subunit beta family

Alternative Names

EC 2.5.1.60; Geranylgeranyl transferase type II subunit beta; geranylgeranyl transferase type-2 subunit beta; GGTase-II-beta; GGTB; Rab geranylgeranyltransferase subunit beta; Rab geranyl-geranyltransferase subunit beta; Rab geranylgeranyltransferase, beta subunit; Rab GG transferase beta; Rab GGTase beta; Type II protein geranyl-geranyltransferase subunit beta

Molecular Weight

Mass (kDA):
36.924 kDA

Genomic Context


Human

Location:	1p31.1
Sequence:	1; NC_000001.11 (75786194..75795090)

Diseases

Carcinoma
Diffuse Large B-cell Lymphoma
Neoplasms
Embryonal Carcinoma
Lymphoma
B-cell Lymphomas

Interacting Proteins

ARAF
B4GALT7
FAM19A1
RABGGTA
TMEM25

WDR4

Pathways

Translation

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RABGGTB

References

PMID: 8706741 by Johannes L., et al. Characterization of the interaction of the monomeric GTP-binding protein Rab3a with geranylgeranyl transferase II.

PMID: 8954794 by van Bokhoven H., et al. cDNA cloning and chromosomal localization of the genes encoding the alpha- and beta-subunits of human Rab geranylgeranyl transferase: the 3' end of the alpha-subunit gene overlaps with the transglutaminase 1 gene promoter.