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- Table of Contents
RalA-binding protein 1 Antibodies
AND RALBP1 ELISA kits, RalA-binding protein 1 Proteins
Many biological assays use antibodies to detect RalA-binding protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RalA-binding protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RalA-binding protein 1 antibodies...
Designing a Western blot for RalA-binding protein 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RALBP1 Western Blot GuideRALBP1 Infographic by Boster Bio
All RALBP1 Products
Product
Figures
Specificity
Applications
Price
Anti-RALBP1 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01403-1
100 μg/vial
Cat # A01403-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # M01403
100 μl
Cat # M01403
100 μl
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01403-4
100 μg/vial
Cat # M01403-4
100 μg/vial
Human
Flow Cytometry, WB
$370
Cat # M01403-2
100 μg/vial
Cat # M01403-2
100 μg/vial
RALBP1 Overview
Facts about RalA-binding protein 1.
RalA-binding protein 1 (RALBP1)
Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the significant ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes.
Can catalyze transport of glutathione conjugates and xenobiotics, and may add to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complicated during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin.
Gene Information
| Human | |
|---|---|
| Gene Name: | RALBP1 |
| Uniprot: | Q15311 |
| Entrez: | 10928 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Dinitrophenyl S-glutathione ATPase; ralA binding protein 1; ralA-binding protein 1,76 kDa Ral-interacting protein; RalBP1; Ral-interacting protein 1; RIP; RIP1; RLIP1; RLIP76DNP-SG ATPase
Molecular Weight
Mass (kDA):
76.063 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 18p11.22 |
| Sequence: | 18; NC_000018.10 (9475513..9538114) |
Subcellular Localizations
Membrane; Peripheral membrane protein.
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Lung
- Non-small Cell Lung Carcinoma
- Lung Neoplasms
- Carcinoma
- Pancreatic Neoplasm
- Malignant Paraganglionic Neoplasm
- Small Cell Carcinoma Of Lung
- Inflammation
- Tumor Angiogenesis
Interacting Proteins
- C1orf216
- CBY1
- CCDC6
- CCL20
- CEP57
- CREBZF
- DLG1
- GPS2
- KANK2
- MSANTD4
Pathways
- Transport
- Endocytosis
- Cell Death
- Drug Resistance
- Angiogenesis
- Cell Proliferation
- Mitosis
- Localization
- Cell Migration
- Necroptosis
- Receptor-mediated Endocytosis
- Cell Cycle
- Exocytosis
PTMs
- Phosphorylation
- Ubiquitination
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RALBP1
bosterbio.com/bosterbio-gene-info-cards/RALBP1
References
PMID: 7673236 by Jullien-Flores V., et al. Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.
PMID: 10924126 by Awasthi S., et al. Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin.