Ran-binding protein 3 Antibodies

AND RANBP3 ELISA kits, Ran-binding protein 3 Proteins

Many biological assays use antibodies to detect Ran-binding protein 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ran-binding protein 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ran-binding protein 3 antibodies...

We validate the specificity of these antibodies to Ran-binding protein 3 by testing them on tissues known to express RANBP3 positively and negatively. Browse below to find the RANBP3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for Ran-binding protein 3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the RANBP3 IHC Guide

RANBP3 Infographic by Boster Bio

All RANBP3 Products

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Specificity

Applications

Price

Anti-RANBP3 Antibody Picoband®

Western blot analysis of RANBP3 using anti-RANBP3 antibody (A06252-1)

IHC analysis of RANBP3 using anti-RANBP3 antibody (A06252-1)

IF analysis of RANBP3 using anti-RANBP3 antibody (A06252-1) and anti-Tubulin Alpha antibody (M03989-3)

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A06252-1
100 µg/vial

Anti-RANBP3 Rabbit Monoclonal Antibody

Western blot analysis of RANBP3 expression in 293 cell lysate

Human, Mouse

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M06252
100 μl/vial

RANBP3 (NM_003624) Human Over-expression Lysate

RANBP3 Human Over-expression Lysates NM_003624

Human

$960
Cat # LS008498
20 µg, 100 µg

RANBP3L (NM_001161429) Human Over-expression Lysate

RANBP3L Human Over-expression Lysates NM_001161429

Human

$628
Cat # LS202151
20 µg, 100 µg

RANBP3 (NM_007322) Human Recombinant Protein

Coomassie blue staining of purified RANBP3 protein

$1249
Cat # PROTQ9H6Z4
20 µg

RANBP3 Overview

Facts about Ran-binding protein 3.

RANBP3 3D structure. Source: alphafold

Ran-binding protein 3 (RANBP3)

Acts as a cofactor for XPO1/CRM1-mediated nuclear export, perhaps as export complex scaffolding protein. Bound to XPO1/CRM1, stabilizes the XPO1/CRM1-cargo interaction.

In the absence of Ran-bound GTP prevents binding of XPO1/CRM1 into the nuclear pore complex. Binds to CHC1/RCC1 and raises the guanine nucleotide exchange activity of CHC1/RCC1.

Gene Information

Human
Gene Name:	RANBP3
Uniprot:	Q9H6Z4
Entrez:	8498

Family

Belongs to:

No superfamily

Alternative Names

DKFZp586I1520; RAN binding protein 3; ran-binding protein 3; RAN-binding protein-3; RanBP3

Molecular Weight

Mass (kDA):
60.21 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (5916139..5978140, complement)

Tissue Specificity

Widely expressed with high levels in testis and heart.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Neoplasms
Cell Transformation, Neoplastic
Liver Carcinoma
Hepatitis
Colonic Neoplasms
Leukemia, T-cell
Hepatitis C, Chronic
Malignant Tumor Of Colon
Hepatitis C
Carcinoma
Adenomatous Polyposis Coli
Malignant Neoplasms

Leukemia
Polyposis
Liver Neoplasms
Janiceps
Colorectal Cancer
Immune System Diseases

Interacting Proteins

PPM1A
RCC1
SMAD2

Pathways

Nuclear Export
Transport
Localization
Nuclear Transport
Nucleocytoplasmic Transport
Rna Interference
Regulation Of Signaling
Protein Transport
Hepatocyte Proliferation
Spermatogenesis

Telophase
Cell Cycle
Chromosome Condensation
Meiosis
Nuclear Import

PTMs

Phosphorylation
Dephosphorylation

Acetylation
Methylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RANBP3

References

PMID: 9637251 by Mueller L., et al. Human RanBP3, a group of nuclear RanGTP binding proteins.

PMID: 11571268 by Englmeier L., et al. RanBP3 influences interactions between CRM1 and its nuclear protein export substrates.