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- Table of Contents
Facts about Ras-related protein Rap-2b.
May play a role in cytoskeletal rearrangements and modulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.
Human | |
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Gene Name: | RAP2B |
Uniprot: | P61225 |
Entrez: | 5912 |
Belongs to: |
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small GTPase superfamily |
MGC20484; Rap2B; RAP2B, member of RAS oncogene family; Ras family small GTP binding protein RAP2B; ras-related protein Rap-2b; small GTP binding protein
Mass (kDA):
20.504 kDA
Human | |
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Location: | 3q25.2 |
Sequence: | 3; NC_000003.12 (153162226..153170627) |
Expressed in red blood cells (at protein level).
Recycling endosome membrane; Lipid-anchor; Cytoplasmic side. Associated with red blood cells-released vesicles.
PMID: 2115998 by Farrell F.X., et al. cDNA sequence of a new ras-related gene (rap2b) isolated from human platelets with sequence homology to rap2.
PMID: 2118648 by Ohmstede C.A., et al. RAP2B: a RAS-related GTP-binding protein from platelets.