Ras-related protein Rap-2b (RAP2B)

Small GTP-binding protein which cycles between a GDP- bound inactive and a GTP-bound active type. Involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1.

May play a role in cytoskeletal rearrangements and modulate cell spreading through activation of the effector TNIK. May regulate membrane vesiculation in red blood cells.