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- Table of Contents
RARG Antibodies
AND RARG ELISA kits, RARG Proteins
Many biological assays use antibodies to detect RARG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RARG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RARG antibodies...
Designing a Western blot for RARG? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RARG Western Blot GuideRARG Infographic by Boster Bio
All RARG Products
Product
Figures
Specificity
Applications
Price
Human, Rat
IF, ICC, WB
$370
Cat # M04250-1
100 μl/vial
Cat # M04250-1
100 μl/vial
Human
$628
Cat # LS005916
20 µg, 100 µg
Cat # LS005916
20 µg, 100 µg
RARG Overview
Facts about Retinoic acid receptor gamma.
Retinoic acid receptor gamma (RARG)
Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and modulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' websites known as DR1-DR5.
In the absence of ligand, acts mainly as an activator of gene expression as a result of weak binding to corepressors. Required for limb bud growth.
Gene Information
| Human | |
|---|---|
| Gene Name: | RARG |
| Uniprot: | P13631 |
| Entrez: | 5916 |
Family
| Belongs to: |
|---|
| nuclear hormone receptor family |
Alternative Names
NR1B3; NR1B3RARC; Nuclear receptor subfamily 1 group B member 3; RAR gamma; RARC; RARG; RAR-gamma; retinoic acid receptor gamma; retinoic acid receptor, gamma
Molecular Weight
Mass (kDA):
50.342 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.13 |
| Sequence: | 12; NC_000012.12 (53210566..53232256, complement) |
Subcellular Localizations
Nucleus. Cytoplasm.
Diseases
- Malignant Neoplasms
- Refractory Anemia With Ringed Sideroblasts
- Neoplasms
- Myeloid Leukemia
- Esophageal Neoplasms
- Adenocarcinoma
- Congenital Absence
- Congenital Abnormality
- Teratogenic Effect
- Leukemia, Myelocytic, Acute
- Crest Syndrome
- Leukemia
- Neoplasm Metastasis
Interacting Proteins
- RXRB
- RXRG
Pathways
- Cell Cycle
- Spermatogenesis
- Meiosis
- Transport
- Cell Proliferation
- Cell Cycle Checkpoint
- Cellular Senescence
- Somitogenesis
- Immune Response
- Palate Development
- Limb Development
- Senescence
- Amino Acid Transport
PTMs
- Isopeptide bond
Research Areas
- Cancer
- Transcription Factors and Regulators
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RARG
bosterbio.com/bosterbio-gene-info-cards/RARG
References
PMID: 2546152 by Krust A., et al. A third human retinoic acid receptor, hRAR-gamma.
PMID: 2172793 by Ishikawa T., et al. A functional retinoic acid receptor encoded by the gene on human chromosome 12.