RBPMS Antibodies

AND RBPMS ELISA kits, RBPMS Proteins

Many biological assays use antibodies to detect RBPMS, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RBPMS in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RBPMS antibodies...

We validate the specificity of these antibodies to RBPMS by testing them on tissues known to express RBPMS positively and negatively. Browse below to find the RBPMS antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RBPMS Infographic by Boster Bio

All RBPMS Products

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Specificity

Applications

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Anti-RBPMS Antibody Picoband®

Western blot analysis of RBPMS using anti-RBPMS antibody (A07130-2)

IHC analysis of RBPMS using anti-RBPMS antibody (A07130-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A07130-2
100 μg/vial

Anti-RBPMS Mouse Monoclonal Antibody [Clone ID: OTI3B7]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RBPMS (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-RBPMS monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human)

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-RBPMS mouse monoclonal antibody

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$523
Cat # M07130
100 µl

RBPMS (NM_001008710) Human Over-expression Lysate

RBPMS Human Over-expression Lysates NM_001008710

Human

$628
Cat # LS011030
20 µg, 100 µg

RBPMS Overview

Facts about RNA-binding protein with multiple splicing.

RBPMS 3D structure. Source: alphafold

RNA-binding protein with multiple splicing (RBPMS)

Acts as a coactivator of transcriptional activity. Required to improve TGFB1/Smad-mediated transactivation.

Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C- terminal SSXS motif, possibly through recruitment of TGFBR1.

Gene Information

Human
Gene Name:	RBPMS
Uniprot:	Q93062
Entrez:	11030

Family

Belongs to:

No superfamily

Alternative Names

FLJ32971; Heart and RRM expressed sequence; Hermes; HERMESRNA-binding protein with multiple splicing; RBP-MS; RNA binding protein with multiple splicing

Molecular Weight

Mass (kDA):
21.802 kDA

Genomic Context


Human

Location:	8p12
Sequence:	8; NC_000008.11 (30384501..30572261)

Tissue Specificity

Ubiquitously expressed, at various levels depending on the isoform and the tissue.

Subcellular Localizations

Nucleus. Cytoplasm. Cytoplasm, P-body. Translocates into cytoplasmic stress granules that probably correspond to P-bodies in response to oxidative stress.

Diseases

Optic Nerve Injuries
Werner Syndrome
Anaplasia
Colonic Pseudo-obstruction
Liver Carcinoma
Intraocular Pressure Disorder
Nerve Degeneration
Neuromuscular Diseases
Glaucoma
Carcinoma
Hypokinesia
Leukemia, Myelocytic, Acute
Myopathy

Myopathies, Visceral
Nerve Transections, Optic
Malignant Neoplasms
Myeloid Leukemia
Leukemia
Liver Neoplasms
Hirschsprung Disease

Pathways

Dedifferentiation
Cell Cycle

PTMs

Phosphorylation

Research Areas

DNA Repair
Mismatch Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RBPMS

References

PMID: 8855282 by Shimamoto A., et al. A unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifs.

PMID: 17099224 by Sun Y., et al. Potentiation of Smad-mediated transcriptional activation by the RNA- binding protein RBPMS.