RENBP Antibodies

AND RENBP ELISA kits, RENBP Proteins

Many biological assays use antibodies to detect RENBP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RENBP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RENBP antibodies...

We validate the specificity of these antibodies to RENBP by testing them on tissues known to express RENBP positively and negatively. Browse below to find the RENBP antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RENBP Infographic by Boster Bio

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RENBP Overview

Facts about N-acylglucosamine 2-epimerase.

RENBP 3D structure. Source: alphafold

N-acylglucosamine 2-epimerase (RENBP)

Catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine.
Binds to renin forming a protein complex called high molecular weight (HMW) renin and inhibits renin activity.

Involved from the N-glycolylneuraminic acid (Neu5Gc) degradation pathway: although human isn't able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded. .

Gene Information

Human
Gene Name:	RENBP
Uniprot:	P51606
Entrez:	5973

Family

Belongs to:

N-acylglucosamine 2-epimerase family

Alternative Names

AGE; EC 5.1.3.8; GlcNAc 2-epimerase; N-acetyl-D-glucosamine 2-epimerase; N-acylglucosamine 2-epimerase; RBP; renin binding protein; Renin-binding protein; RNBP

Molecular Weight

Mass (kDA):
48.831 kDA

Genomic Context


Human

Location:	Xq28
Sequence:	X; NC_000023.11 (153935263..153944643, complement)

Diseases

Hypertensive Disease
Essential Hypertension
Myopathy
Neoplasms
Inborn Errors Of Metabolism
Sialuria
Pituitary Diseases
Inclusion Body Myositis (disorder)
Nephroblastoma
Inflammation
Muscular Dystrophy
Hypotension Adverse Event
Distal Muscular Dystrophies

Myocardial Ischemia
Disease Of Adrenal Medulla
Osteitis Deformans
Weakness
Macule
Dementia
Neuromuscular Diseases

Pathways

Localization
Secretion
Cell Adhesion
Secretory Pathway
Cell Proliferation
Translation
Exocytosis

Pathogenesis
Excretion

PTMs

Cleavage

Dephosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RENBP

References

PMID: 1723410 by Inoue H., et al. Genetic and molecular properties of human and rat renin-binding proteins with reference to the function of the leucine zipper motif.

PMID: 9990133 by Takahashi S., et al. Human renin-binding protein is the enzyme N-acetyl-D-glucosamine 2- epimerase.