Replication initiator 1 Antibodies

AND REPIN1 ELISA kits, Replication initiator 1 Proteins

Many biological assays use antibodies to detect Replication initiator 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Replication initiator 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Replication initiator 1 antibodies...

We validate the specificity of these antibodies to Replication initiator 1 by testing them on tissues known to express REPIN1 positively and negatively. Browse below to find the REPIN1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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REPIN1 Infographic by Boster Bio

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AP4 (REPIN1) (NM_013400) Human Over-expression Lysate

AP4 (REPIN1) Human Over-expression Lysates NM_001099696

Human

$628
Cat # LS029803
20 µg, 100 µg

REPIN1 Overview

Facts about Replication initiator 1.

REPIN1 3D structure. Source: alphafold

Replication initiator 1 (REPIN1)

Sequence-specific double-stranded DNA-binding protein required for initiation of chromosomal DNA replication. Binds on 5'-ATT-3' reiterated sequences downstream of the origin of bidirectional replication (OBR) and a second, homologous ATT series of reverse orientation situated within the OBR zone.

Facilitates DNA bending. .

Gene Information

Human
Gene Name:	REPIN1
Uniprot:	Q9BWE0
Entrez:	29803

Family

Belongs to:

No superfamily

Alternative Names

60 kDa origin-specific DNA-binding protein; 60 kDa replication initiation region protein; ATT-binding protein; DHFR oribeta-binding protein RIP60; H_DJ0584D14.12; replication initiation region protein (60kD); replication initiator 1; RIP60AP4; Zfp464; zinc finger protein 464 (RIP60); Zinc finger protein 464; zinc finger protein AP4; zinc finger proten AP4; ZNF464

Molecular Weight

Mass (kDA):
63.575 kDA

Genomic Context


Human

Location:	7q36.1
Sequence:	7; NC_000007.14 (150368096..150374044)

Subcellular Localizations

Nucleus.

Diseases

Metabolic Diseases
Metabolic Syndrome X
Obesity
Insulin Resistance
Diabetes Mellitus, Insulin-dependent
Down Syndrome

Diabetes Mellitus

Pathways

Transport
Regulation Of Cell Size
Dna Replication
Fatty Acid Transport
Cellular Localization
Rna Interference
Glucose Transport

Localization

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/REPIN1

References

PMID: 10606657 by Houchens C.R., et al. The dhfr oribeta-binding protein RIP60 contains 15 zinc fingers: DNA binding and looping by the central three fingers and an associated proline-rich region.

PMID: 2174103 by Dailey L., et al. Purification of RIP60 and RIP100, mammalian proteins with origin- specific DNA-binding and ATP-dependent DNA helicase activities.