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- Table of Contents
RFC2 Antibodies
AND RFC2 ELISA kits, RFC2 Proteins
Many biological assays use antibodies to detect RFC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RFC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RFC2 antibodies...
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RFC2 Infographic by Boster Bio
All RFC2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M07724
100 µl
Cat # M07724
100 µl
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A07724-1
100 µg/vial
Cat # A07724-1
100 µg/vial
RFC2 Overview
Facts about Replication factor C subunit 2.
Replication factor C subunit 2 (RFC2)
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. This subunit binds ATP (By similarity).
. .
Gene Information
| Human | |
|---|---|
| Gene Name: | RFC2 |
| Uniprot: | P35250 |
| Entrez: | 5982 |
Family
| Belongs to: |
|---|
| activator 1 small subunits family |
Alternative Names
A1 40 kDa subunit; A1; Activator 1 40 kDa subunit; Activator 1 subunit 2; MGC3665; replication factor C (activator 1) 2, 40kDa; replication factor C 2; Replication factor C 40 kDa subunit; replication factor C subunit 2; RF-C 40 kDa subunit; RFC40replication factor C (activator 1) 2 (40kD)
Molecular Weight
Mass (kDA):
39.157 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q11.23 |
| Sequence: | 7; NC_000007.14 (74231502..74254458, complement) |
Subcellular Localizations
Nucleus.
Diseases
- Williams Syndrome
- Neoplasms
- Carcinoma
- Infantile Hypercalcemia
- Malignant Paraganglionic Neoplasm
- Haploinsufficiency
- Carcinogenesis
- Cell Transformation, Neoplastic
- Glioblastoma
- Brain Neoplasms
- Hyperplasia
- Hypercalcemia
Interacting Proteins
- PRKAR1A
- RFC1
- RFC4
Pathways
- Dna Replication
- Cell Cycle
- Dna Damage Checkpoint
- Dna Repair
- S Phase
- Cell Growth
- Transport
- Nuclear Transport
- Cell Division
- Cell Proliferation
- Mitosis
- Localization
- Dna Replication Checkpoint
PTMs
Research Areas
- Cell Cycle and Replication
- DNA Repair
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RFC2
bosterbio.com/bosterbio-gene-info-cards/RFC2
References
PMID: 1313560 by Chen M., et al. Sequence and expression in Escherichia coli of the 40-kDa subunit of activator 1 (replication factor C) of HeLa cells.
PMID: 11003705 by Martindale D.W., et al. Comparative genomic sequence analysis of the Williams syndrome region (LIMK1-RFC2) of human chromosome 7q11.23.