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- Table of Contents
Facts about GTP-binding protein Rit2.
Binds and exchanges GTP and GDP.
Binds and modulates the activation of POU4F1 as gene expression regulator..
| Human | |
|---|---|
| Gene Name: | RIT2 |
| Uniprot: | Q99578 |
| Entrez: | 6014 |

| Belongs to: |
|---|
| small GTPase superfamily |

GTP-binding protein Rit2; GTP-binding protein Roc2; Ras-like protein expressed in neurons; Ras-like without CAAX 2; Ras-like without CAAX protein 2; RIBA; Ric (Drosophila)-like, expressed in neurons; Ric-like, expressed in neurons; RIN; Rit2; ROC2
Mass (kDA):
24.668 kDA

| Human | |
|---|---|
| Location: | 18q12.3 |
| Sequence: | 18; NC_000018.10 (42743218..43115692, complement) |
Neuron-specific.
Nucleus. Cell membrane. Colocalizes with PLXNB3 at the plasma membrane (PubMed:16122393).






PMID: 8824319 by Lee C.H.J., et al. Rin, a neuron-specific and calmodulin-binding small G-protein, and Rit define a novel subfamily of ras proteins.
PMID: 8918462 by Wes P.D., et al. RIC, a calmodulin-binding Ras-like GTPase.