RND1 Antibodies

AND RND1 ELISA kits, RND1 Proteins

Many biological assays use antibodies to detect RND1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RND1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RND1 antibodies...

We validate the specificity of these antibodies to RND1 by testing them on tissues known to express RND1 positively and negatively. Browse below to find the RND1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RND1 Infographic by Boster Bio

All RND1 Products

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Figures

Specificity

Applications

Price

Anti-RND1 Antibody Picoband®

7 Q&As

Western blot analysis of RND1 using anti-RND1 antibody (A06347)

Human, Mouse

$370
Cat # A06347
100 μg/vial

RND1 (NM_014470) Human Recombinant Protein

Coomassie blue staining of purified RND1 protein

$1249
Cat # PROTQ92730
20 µg

Anti-RND1 Mouse Monoclonal Antibody [Clone ID: OTI1C3]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY RND1 (Right lane) cDNA for 48 hrs and lysed

HEK293T cells transfected with either RND1 (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-RND1 antibody (M06347)

Human, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M06347
100 µl

RND1 (NM_014470) Human Over-expression Lysate

Human

$628
Cat # LS027289
20 µg, 100 µg

RND1 Overview

Facts about Rho-related GTP-binding protein Rho6.

RND1 3D structure. Source: alphafold

Rho-related GTP-binding protein Rho6 (RND1)

Lacks intrinsic GTPase activity. Has a very low affinity for GDP, and constitutively binds GTP.

Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments.

Gene Information

Human
Gene Name:	RND1
Uniprot:	Q92730
Entrez:	27289

Family

Belongs to:

small GTPase superfamily

Alternative Names

ARHS; GTP-binding protein; ras homolog gene family, member S; Rho family GTPase 1FLJ42294; RHO6; rho-related GTP-binding protein Rho6; RHOS; Rnd1

Molecular Weight

Mass (kDA):
26.056 kDA

Genomic Context


Human

Location:	12q13.12
Sequence:	12; NC_000012.12 (48857145..48865870, complement)

Tissue Specificity

Mostly expressed in brain and liver.

Subcellular Localizations

Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton.

Diseases

Tissue Adhesions
Neoplasm Metastasis
Malignant Neoplasms
Neoplasms
Nervousness
Cell Invasion
Nervous System Disorder
Premature Obstetric Labor
Wolfram Syndrome
Feeling Despair
Mood Disorders
Varicosity

Malignant Neoplasm Of Breast
Carcinoma 256, Walker
Neoplasm Invasiveness
Degenerative Polyarthritis
Depression And Suicide
Cardiovascular Diseases

Interacting Proteins

GRB7
PLXNB1
PLXNB2

Pathways

Cell Adhesion
Axon Guidance
Cell Migration
Sensitization
Cell Cycle
Localization
Dendrite Development
Translation
Cell Motility
Receptor Clustering
Cell Growth
Regulation Of Dendrite Development
Cell Fate Specification

Cytoskeleton Organization
Axon Extension
Mrna Transcription
Estrus
Segmentation
Oncogenesis
Actin Cytoskeleton Organization

PTMs

Phosphorylation
Farnesylation

Prenylation
Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RND1

References

PMID: 9531558 by Nobes C.D., et al. A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion.

PMID: 11095956 by Aoki J., et al. Rnd1, a novel rho family GTPase, induces the formation of neuritic processes in PC12 cells.