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- Table of Contents
RRM1 Antibodies
AND RRM1 ELISA kits, RRM1 Proteins
Many biological assays use antibodies to detect RRM1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RRM1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RRM1 antibodies...
Designing a Western blot for RRM1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the RRM1 Western Blot GuideRRM1 Infographic by Boster Bio
All RRM1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01764
100 μl
Cat # M01764
100 μl
Human, Mouse, Rat
ELISA, IP, IF, WB
$146
Cat # M01764-3
20μL, 40μL, 100μL, 200μL
Cat # M01764-3
20μL, 40μL, 100μL, 200μL
RRM1 Overview
Facts about Ribonucleoside-diphosphate reductase large subunit.
Ribonucleoside-diphosphate reductase large subunit (RRM1)
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | RRM1 |
| Uniprot: | P23921 |
| Entrez: | 6240 |
Family
| Belongs to: |
|---|
| ribonucleoside diphosphate reductase large chain family |
Alternative Names
EC 1.17.4.1; R1; ribonucleoside-diphosphate reductase large subunit; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunit; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase M1; ribonucleotide reductase, large subunit; ribonucleotide reductase, R1 subunit; RIR1; RR1
Molecular Weight
Mass (kDA):
90.07 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11p15.4 |
| Sequence: | 11; NC_000011.10 (4094685..4138932) |
Subcellular Localizations
Cytoplasm.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Lung
- Neoplasms
- Non-small Cell Lung Carcinoma
- Lung Neoplasms
- Adenocarcinoma
- Carcinoma
- Malignant Neoplasm Of Pancreas
- Pancreatic Neoplasm
- Neoplasm Metastasis
- Malignant Neoplasm Of Breast
- Congenital Dyserythropoietic Anemia
Interacting Proteins
- RRM2
Pathways
- Dna Repair
- Localization
- Translation
- Cell Proliferation
- Cell Cycle
- Transport
- Pathogenesis
- Methylation
- Rna Interference
- Nuclear Export
- Reverse Transcription
- Cell Growth
PTMs
- Phosphorylation
- Cleavage
- Methylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RRM1
bosterbio.com/bosterbio-gene-info-cards/RRM1
References
PMID: 1840662 by Parker N.J., et al. Human M1 subunit of ribonucleotide reductase: cDNA sequence and expression in stimulated lymphocytes.
PMID: 1627826 by Pavloff N., et al. Sequence analysis of the large and small subunits of human ribonucleotide reductase.