Rotatin Antibodies

AND RTTN ELISA kits, Rotatin Proteins

Many biological assays use antibodies to detect Rotatin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Rotatin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Rotatin antibodies...

We validate the specificity of these antibodies to Rotatin by testing them on tissues known to express RTTN positively and negatively. Browse below to find the RTTN antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RTTN Infographic by Boster Bio

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RTTN Overview

Facts about Rotatin.

RTTN 3D structure. Source: alphafold

Rotatin (RTTN)

Involved in the genetic cascade that modulates left-right specification. Plays a role in the maintenance of a normal ciliary structure.

Required for proper asymmetric expression of NODAL, LEFTY and PITX2. .

Gene Information

Human
Gene Name:	RTTN
Uniprot:	Q86VV8
Entrez:	25914

Family

Belongs to:

No superfamily

Alternative Names

DKFZp434G145; FLJ26356; FLJ39085; MSSP; PMGYS; Rotatin; RTTN

Molecular Weight

Mass (kDA):
248.63 kDA

Genomic Context


Human

Location:	18q22.2
Sequence:	18; NC_000018.10 (70003031..70205726, complement)

Subcellular Localizations

Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Colocalizes with the basal bodies at the primary cilium.

Diseases

Mutation Abnormality
Malformations Of Cortical Development
Congenital Abnormality
Polymicrogyria
Hemorrhage
Vertical Disease Transmission

Hiv Infections

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RTTN

References

PMID: 22939636 by Kheradmand Kia S., et al. RTTN mutations link primary cilia function to organization of the human cerebral cortex.