RGS3 Antibodies

AND RGS3 ELISA kits, RGS3 Proteins

Many biological assays use antibodies to detect RGS3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with RGS3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop RGS3 antibodies...

We validate the specificity of these antibodies to RGS3 by testing them on tissues known to express RGS3 positively and negatively. Browse below to find the RGS3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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RGS3 Infographic by Boster Bio

All RGS3 Products

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Anti-RGS3 Antibody Picoband®

4 Q&As

Anti-RGS3 antibody, PA2050, Western blottingLane 1: Rat Testis Tissue LysateLane 2: Rat Brain Tissue LysateLane 3: Rat Spleen Tissue LysateLane 4: HELA Cell LysateLane 5: U87 Cell Lysate

Anti-RGS3 antibody, PA2050, IHC(P)IHC(P): Rat Intestine Tissue

Human, Mouse, Rat

IHC, WB

$370
Cat # PA2050
100 μg/vial

RGS3 (NM_134427) Human Recombinant Protein

Coomassie blue staining of purified RGS3 protein

$1062
Cat # PROTP49796
20 µg

RGS3 (NM_130795) Human Over-expression Lysate

RGS3 Human Over-expression Lysates NM_017790

Human

$628
Cat # LS005998
20 µg, 100 µg

RGS3 Overview

Facts about Regulator of G-protein signaling 3.

RGS3 3D structure. Source: alphafold

Regulator of G-protein signaling 3 (RGS3)

Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G- protein-mediated release of inositol phosphates and activation of MAP kinases.

Gene Information

Human
Gene Name:	RGS3
Uniprot:	P49796
Entrez:	5998

Family

Belongs to:

No superfamily

Alternative Names

C2PA; FLJ20370; FLJ31516; FLJ90496; PDZ-RGS3; regulator of G-protein signaling 3; regulator of G-protein signalling 3; RGP3

Molecular Weight

Mass (kDA):
132.336 kDA

Genomic Context


Human

Location:	9q32
Sequence:	9; NC_000009.12 (113444730..113597743)

Subcellular Localizations

Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Long isoforms are cytoplasmic and associated with the plasma membrane (PubMed:9858594). Short isoforms are nuclear (PubMed:10749886).

Diseases

Heart Failure
Pertussis
Hypertrophy
Malignant Neoplasms
Pituitary Diseases
Cardiac Hypertrophy
Nervousness
Neoplasms
Chimera Disorder
Tissue Adhesions
Cholangiocarcinoma
Sclerosis
Urinary Bladder Diseases

Peripheral Nerve Injuries
Malignant Neoplasm Of Breast
Glioma
Myeloid Leukemia, Chronic
Arteriovenous Malformation
Neoplasm Invasiveness
Carcinoma

Interacting Proteins

ACD
GORASP2
PLSCR1

Pathways

Localization
Cell Migration
Transport
Chemotaxis
Secretion
Cell Activation
Neurogenesis
Cell Division
Cell Cycle
Synaptic Transmission
Cell Growth
Regulation Of Signaling
B Cell Activation

Spermatogenesis
Neurotransmitter Secretion
Negative Regulation Of Cell Activation
Translation
Cell Motility
Cell Differentiation
Mating

PTMs

Phosphorylation
Isgylation

Palmitoylation
Ubiquitination

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/RGS3

References

PMID: 8602223 by Druey K.M., et al. Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family.

PMID: 12036301 by Kehrl J.H., et al. Additional 5' exons in the RGS3 locus generate multiple mRNA transcripts, one of which accounts for the origin of human PDZ-RGS3.