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SARS1 Antibodies
AND SARS1 ELISA kits, SARS1 Proteins
Many biological assays use antibodies to detect SARS1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SARS1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SARS1 antibodies...
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SARS1 Infographic by Boster Bio
All SARS1 Products
Product
Figures
Specificity
Applications
Price
Human
$628
Cat # LS006301
20 µg, 100 µg
Cat # LS006301
20 µg, 100 µg
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00501-1
100 μg/vial
Cat # A00501-1
100 μg/vial
SARS1 Overview
Facts about Serine--tRNA ligase, cytoplasmic.
Serine--tRNA ligase, cytoplasmic (SARS1)
Catalyzes the attachment of serine to tRNA(Ser) at a two-step reaction: serine is triggered by ATP to form Ser- AMP and then transferred to the acceptor end of tRNA(Ser) (PubMed:22353712, PubMed:24095058, PubMed:9431993, PubMed:26433229, PubMed:28236339). Is probably also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which is converted to selenocysteinyl-tRNA(Sec) (PubMed:9431993, PubMed:26433229, PubMed:28236339).
In the nucleus, binds to the VEGFA core promoter and prevents MYC binding and transcriptional activation by MYC (PubMed:24940000). Recruits SIRT2 to the VEGFA promoter, promoting deacetylation of histone H4 at'Lys-16' (H4K16).
Gene Information
| Human | |
|---|---|
| Gene Name: | SARS1 |
| Uniprot: | P49591 |
| Entrez: | 6301 |
Family
| Belongs to: |
|---|
| class-II aminoacyl-tRNA synthetase family |
Alternative Names
Serine--tRNA ligase, cytoplasmic
Molecular Weight
Mass (kDA):
58.777 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p13.3 |
| Sequence: | 1; NC_000001.11 (109213893..109238182) |
Tissue Specificity
Brain.
Subcellular Localizations
Cytoplasm. Nucleus. Predominantly cytoplasmic, but a minor proportion is also found in the nucleus.
PTMs
- Acetylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SARS1
bosterbio.com/bosterbio-gene-info-cards/SARS1
References
PMID: 9431993 by Vincent C., et al. Genomic organization, cDNA sequence, bacterial expression, and purification of human seryl-tRNA synthase.
PMID: 19423848 by Fukui H., et al. Noncanonical activity of seryl-tRNA synthetase is involved in vascular development.