SCML1 Antibodies

AND SCML1 ELISA kits, SCML1 Proteins

Many biological assays use antibodies to detect SCML1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SCML1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SCML1 antibodies...

We validate the specificity of these antibodies to SCML1 by testing them on tissues known to express SCML1 positively and negatively. Browse below to find the SCML1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SCML1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SCML1 IHC Guide

SCML1 Infographic by Boster Bio

All SCML1 Products

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Product

Figures

Specificity

Applications

Price

Anti-SCML1 Antibody Picoband®

Western blot analysis of SCML1 using anti-SCML1 antibody (A12084-1)

IHC analysis of SCML1 using anti-SCML1 antibody (A12084-1)

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A12084-1
100 μg/vial

SCML1 (NM_001037540) Human Over-expression Lysate

SCML1 Human Over-expression Lysates NM_001037535

Human

$628
Cat # LS006322
20 µg, 100 µg

SCML1 (NM_001037540) Human Recombinant Protein

Coomassie blue staining of purified SCML1 protein

$1062
Cat # PROTQ9UN30
20 µg

SCML1 Overview

Facts about Sex comb on midleg-like protein 1.

SCML1 3D structure. Source: alphafold

Sex comb on midleg-like protein 1 (SCML1)

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes during development.

May be involved in spermatogenesis during sexual maturation (By similarity). .

Gene Information

Human
Gene Name:	SCML1
Uniprot:	Q9UN30
Entrez:	6322

Family

Belongs to:

SCM family

Alternative Names

sex comb on midleg (Drosophila)-like 1; sex comb on midleg-like 1 (Drosophila); sex comb on midleg-like protein 1

Molecular Weight

Mass (kDA):
37.447 kDA

Genomic Context


Human

Location:	Xp22.13
Sequence:	X; NC_000023.11 (17737449..17754988)

Tissue Specificity

Ubiquitous. Expressed in fetal and adult tissues.

Subcellular Localizations

Nucleus.

Diseases

Nance-horan Syndrome
Cataract
Congenital Abnormality
Tooth Abnormalities
Retinal Degeneration
Genetic Diseases, X-linked

Eye Diseases, Hereditary

Pathways

Spermatogenesis
Methylation
Fertilization
Regulation Of Gene Expression

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SCML1

References

PMID: 9570953 by van de Vosse E., et al. Characterization of SCML1, a new gene in Xp22, with homology to developmental polycomb genes.

PMID: 18601738 by Wu H.-H., et al. Adaptive evolution of SCML1 in primates, a gene involved in male reproduction.