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- Table of Contents
Facts about SEC14-like protein 2.
Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols.
| Human | |
|---|---|
| Gene Name: | SEC14L2 |
| Uniprot: | O76054 |
| Entrez: | 23541 |

| Belongs to: |
|---|
| No superfamily |

C22orf6; hTAP; KIAA1186SEC14 (S. cerevisiae)-like 2; KIAA1658SPFAlpha-tocopherol-associated protein; SEC14-like 2 (S. cerevisiae); SEC14-like protein 2; Squalene transfer protein; Supernatant protein factor; TAP1; TAPMGC65053; tocopherol-associated protein
Mass (kDA):
46.145 kDA

| Human | |
|---|---|
| Location: | 22q12.2 |
| Sequence: | 22; NC_000022.11 (30396941..30425303) |
Widely expressed. Strong expression in liver, brain and prostate.
Cytoplasm. Nucleus. Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.





PMID: 10829015 by Zimmer S., et al. A novel human tocopherol-associated protein: cloning, in vitro expression, and characterization.
PMID: 11444841 by Yamauchi J., et al. Tocopherol-associated protein is a ligand-dependent transcriptional activator.