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- Table of Contents
Semaphorin-4A Antibodies
AND Sema4a ELISA kits, Semaphorin-4A Proteins
Many biological assays use antibodies to detect Semaphorin-4A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Semaphorin-4A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Semaphorin-4A antibodies...
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Sema4a Infographic by Boster Bio
All Sema4a Products
Product
Figures
Specificity
Applications
Price
Human, Monkey, Mouse, Rat
ELISA, IF, IHC, WB
$399
Cat # A06779-1
100μl
Cat # A06779-1
100μl
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A06779-3
100 µg/vial
Cat # A06779-3
100 µg/vial
Sema4a Overview
Facts about Semaphorin-4A.
Semaphorin-4A (Sema4a)
Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an significant role in cell-cell signaling. Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thus contributes to adaptive immunity.
Promotes phosphorylation of TIMD2. Inhibits angiogenesis.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Sema4a |
| Uniprot: | Q62178 |
| Entrez: | 20351 |
Family
| Belongs to: |
|---|
| semaphorin family |
Alternative Names
CORD10; RP35; Sema B; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and shortcytoplasmic domain, (semaphorin) 4A; SEMA4A; SEMAB; Semaphorin 4A; semaphorin-4A; semaphorin-B; SEMB; SEMBFLJ12287
Molecular Weight
Mass (kDA):
83.421 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 3|3 F1 |
| Sequence: | 3; |
Diseases
- Nervousness
- Retinal Degeneration
- Autoimmune Reaction
- Tumor Angiogenesis
- Autoimmune Diseases
- Retinitis Pigmentosa
- Experimental Autoimmune Encephalomyelitis
- Autoimmunity
- Inflammation
- Communicable Diseases
- Asthma
Pathways
- Immune Response
- Axon Guidance
- Cell Activation
- Angiogenesis
- Cell Migration
- T Cell Activation
- Cell Death
- Pathogenesis
- Cell Adhesion
- Response To Lipopolysaccharide
- Circadian Rhythm
- Signal Transmission
- Localization
PTMs
- Disulfide bond
Research Areas
- Neuroscience
- Vision
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sema4a
bosterbio.com/bosterbio-gene-info-cards/Sema4a
References
PMID: 7748561 by Pueschel A.W., et al. Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension.
PMID: 12374982 by Kumanogoh A., et al. Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2.