Serpin B8 Antibodies

AND SERPINB8 ELISA kits, Serpin B8 Proteins

Many biological assays use antibodies to detect Serpin B8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Serpin B8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Serpin B8 antibodies...

We validate the specificity of these antibodies to Serpin B8 by testing them on tissues known to express SERPINB8 positively and negatively. Browse below to find the SERPINB8 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SERPINB8 Infographic by Boster Bio

All SERPINB8 Products

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SERPINB8 (NM_001031848) Human Recombinant Protein

Coomassie blue staining of purified SERPINB8 protein

$1249
Cat # PROTP50452
20 µg

Anti-SERPINB8 Mouse Monoclonal Antibody [Clone ID: OTI8F10]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINB8 (Right lane) cDNA for 48 hrs and lysed

Western blot analysis of extracts (35ug) from 2 different cell lines by using anti-SERPINB8 monoclonal antibody (1:500)

Human

$523
Cat # M11265
100 µl

SERPINB8 (NM_002640) Human Over-expression Lysate

SERPINB8 Human Over-expression Lysates NM_001031848

Human

$628
Cat # LS005271
20 µg, 100 µg

Anti-SERPINB8 Antibody Picoband®

Western blot analysis of SERPINB8 using anti-SERPINB8 antibody (A11265-1)

IF analysis of SERPINB8 using anti-SERPINB8 antibody (A11265-1)

Flow Cytometry analysis of JK cells using anti-SERPINB8 antibody (A11265-1)

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A11265-1
100 µg/vial

SERPINB8 Overview

Facts about Serpin B8.

SERPINB8 3D structure. Source: alphafold

Serpin B8 (SERPINB8)

Has an essential part in epithelial desmosome-mediated cell-cell adhesion. .

Gene Information

Human
Gene Name:	SERPINB8
Uniprot:	P50452
Entrez:	5271

Family

Belongs to:

serpin family

Alternative Names

CAP2; CAP-2; CAP2clade B (ovalbumin), member 8; Cytoplasmic antiproteinase 2; NK10; Peptidase inhibitor 8; PI8; PI-8; protease inhibitor 8 (ovalbumin type); Serpin B8; serpin peptidase inhibitor, clade B (ovalbumin), member 8

Molecular Weight

Mass (kDA):
42.767 kDA

Genomic Context


Human

Location:	18q22.1
Sequence:	18; NC_000018.10 (63970029..64019779)

Subcellular Localizations

Cytoplasm.

Diseases

Neoplasms
Pituitary Diseases
Psoriasis
Arthritis
Inflammation
Islet Cell Tumor
Disease Of Adrenal Medulla
Cowpox
Insulinoma
Infectious Mononucleosis
Malignant Neoplasm Of Breast
Hypokinesia

Fibrosis
Malignant Neoplasms
Pancreatic Neoplasm
Mammary Neoplasms
Arthritis, Psoriatic
Ureteral Obstruction
Adenocarcinoma

Pathways

Coagulation
Regeneration
Cell Proliferation
Cell Migration
Fibrinolysis
Platelet Activation
Complement Activation
Autolysis
Pathogenesis

Hemostasis
Localization
Platelet Aggregation

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SERPINB8

References

PMID: 8530382 by Sprecher C.A., et al. Molecular cloning, expression, and partial characterization of two novel members of the ovalbumin family of serine proteinase inhibitors.

PMID: 27476651 by Pigors M., et al. Loss-of-function mutations in SERPINB8 linked to exfoliative ichthyosis with impaired mechanical stability of intercellular adhesions.