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- Table of Contents
Splicing factor 1 Antibodies
AND SF1 ELISA kits, Splicing factor 1 Proteins
Many biological assays use antibodies to detect Splicing factor 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Splicing factor 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Splicing factor 1 antibodies...
Designing a Western blot for Splicing factor 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SF1 Western Blot GuideSF1 Infographic by Boster Bio
All SF1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01009-2
100 μg/vial
Cat # M01009-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M01009-1
100 μg/vial
Cat # M01009-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PA1864
100 μg/vial
Cat # PA1864
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01009
100 μg/vial
Cat # A01009
100 μg/vial
Human
$628
Cat # LS007536
20 µg, 100 µg
Cat # LS007536
20 µg, 100 µg
Human, Mouse
ELISA
$540
Cat # EKC2119
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2119
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse
ELISA
$480
Cat # EKC1517
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1517
1 kit, containing one 96-well plate and all necessary reagents
SF1 Overview
Facts about Splicing factor 1.
Splicing factor 1 (SF1)
Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of this pre-mRNA.
May act as transcription repressor. .
Gene Information
| Human | |
|---|---|
| Gene Name: | SF1 |
| Uniprot: | Q15637 |
| Entrez: | 7536 |
Family
| Belongs to: |
|---|
| BBP/SF1 family |
Alternative Names
Mammalian branch point-binding protein; mBBP; splicing factor 1; Transcription factor ZFM1; ZFM1BBP; Zinc finger gene in MEN1 locus; Zinc finger protein 162D11S636; ZNF162MBBP
Molecular Weight
Mass (kDA):
68.33 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 11q13.1 |
| Sequence: | 11; NC_000011.10 (64764604..64778844, complement) |
Tissue Specificity
Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart.
Subcellular Localizations
Nucleus.
Diseases
- Neoplasms
- Disorders Of Sex Development
- Congenital Abnormality
- Hypoplasia
- Pituitary Diseases
- Adrenal Gland Hypofunction
- Gonadal Dysgenesis
- Congenital Absence Of Adrenal Gland
- Congenital Hypoplasia Of Adrenal Gland
- Hypogonadism
- Malignant Neoplasms
- Hypogonadotropic Hypogonadism
- Carcinoma
Interacting Proteins
- ABL2
- CEP104
- Cep104
- CHERP
- Cherp
- CIAO1
- Cltc
- DDX17
- DDX5
- FAM168A
Pathways
- Sex Determination
- Sex Differentiation
- Localization
- Cell Differentiation
- Gonad Development
- Secretion
- Transport
- Sertoli Cell Differentiation
- Translation
- Cell Proliferation
- Cell Cycle
- Spermatogenesis
- Energy Homeostasis
PTMs
- Cleavage
- Phosphorylation
- Hydroxylation
- Oxidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SF1
bosterbio.com/bosterbio-gene-info-cards/SF1
References
PMID: 8752089 by Arning S., et al. Mammalian splicing factor SF1 is encoded by variant cDNAs and binds to RNA.
PMID: 9192847 by Caslini C., et al. Identification of two novel isoforms of the ZNF162 gene: a growing family of signal transduction and activator of RNA proteins.