SF3A2 Antibodies

AND SF3A2 ELISA kits, SF3A2 Proteins

Many biological assays use antibodies to detect SF3A2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SF3A2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SF3A2 antibodies...

We validate the specificity of these antibodies to SF3A2 by testing them on tissues known to express SF3A2 positively and negatively. Browse below to find the SF3A2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for SF3A2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the SF3A2 IHC Guide

SF3A2 Infographic by Boster Bio

All SF3A2 Products

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Anti-SF3A2 Antibody Picoband®

Western blot analysis of SF3A2 using anti-SF3A2 antibody (A11289-2)

IHC analysis of SF3A2 using anti-SF3A2 antibody (A11289-2)

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A11289-2
100 µg/vial

SF3A2 Overview

Facts about Splicing factor 3A subunit 2.

SF3A2 3D structure. Source: alphafold

Splicing factor 3A subunit 2 (SF3A2)

Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA.

May also be involved in the assembly of the 'E' complex. .

Gene Information

Human
Gene Name:	SF3A2
Uniprot:	Q15428
Entrez:	8175

Family

Belongs to:

SF3A2 family

Alternative Names

pre-mRNA splicing factor SF3A, subunit 2; PRP11; PRPF11; SAP 62; SAP62Prp11; SF3a66splicing factor 3a, subunit 2, 66kD; spliceosome associated protein 62; Spliceosome-associated protein 62; splicing factor 3A subunit 2; splicing factor 3a, subunit 2, 66kDa

Molecular Weight

Mass (kDA):
49.256 kDA

Genomic Context


Human

Location:	19p13.3
Sequence:	19; NC_000019.10 (2236824..2248655)

Subcellular Localizations

Nucleus.

Diseases

Mayer-rokitansky-kuster-hauser Syndrome
Pituitary Diseases

Interacting Proteins

CDC5L
DHX15
HSPA8
RBM17
SF1

SF3A1
SNRPA1
SNRPE
SNRPF

Pathways

Translation
Sex Differentiation
Male Sex Differentiation
V(d)j Recombination
Rna Splicing

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SF3A2

References

PMID: 8211113 by Bennett M., et al. Correspondence between a mammalian spliceosome component and an essential yeast splicing factor.

PMID: 9710584 by Yan D., et al. CUS2, a yeast homolog of human Tat-SF1, rescues function of misfolded U2 through an unusual RNA recognition motif.