SFMBT1 Antibodies

AND SFMBT1 ELISA kits, SFMBT1 Proteins

Many biological assays use antibodies to detect SFMBT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SFMBT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SFMBT1 antibodies...

We validate the specificity of these antibodies to SFMBT1 by testing them on tissues known to express SFMBT1 positively and negatively. Browse below to find the SFMBT1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SFMBT1 Infographic by Boster Bio

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SFMBT1 (NM_001005159) Human Over-expression Lysate

SFMBT1 Human Over-expression Lysates NM_001005158

Human

$628
Cat # LS051460
20 µg, 100 µg

SFMBT1 Overview

Facts about Scm-like with four MBT domains protein 1.

SFMBT1 3D structure. Source: alphafold

Scm-like with four MBT domains protein 1 (SFMBT1)

Histone-binding protein, which is part of various corepressor complexes. Mediates the recruitment of corepressor complexes to target genes, followed by chromatin compaction and repression of transcription.

Plays a role during myogenesis: required for the maintenance of undifferentiated states of myogenic progenitor cells via interaction with MYOD1. Interaction with MYOD1 leads to the recruitment of related corepressors and silencing of MYOD1 target genes.

Gene Information

Human
Gene Name:	SFMBT1
Uniprot:	Q9UHJ3
Entrez:	51460

Family

Belongs to:

No superfamily

Alternative Names

DKFZp434L243; Renal ubiquitous protein 1; RU1scm-like with four MBT domains protein 1; Scm-like with four mbt domains 1; Scm-related gene containing four mbt domains; Scm-related gene product containing four mbt domains; SFMBT

Molecular Weight

Mass (kDA):
98.141 kDA

Genomic Context


Human

Location:	3p21.1
Sequence:	3; NC_000003.12 (52899209..53046655, complement)

Tissue Specificity

Expressed in all cell lines and normal tissues tested, including the thymus.

Subcellular Localizations

Nucleus.

Diseases

Mutation Abnormality
Hydrocephalus, Normal Pressure
Dementia
Hydrocephalus
Gait Abnormality
Hypertensive Disease
Cardiovascular Diseases
Radiation Chimera Disorder

Pathological Process
Hyperphosphatemia
Hypoglycemia

Interacting Proteins

HIST3H3
PHC2
ZCCHC10

Pathways

Ion Homeostasis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SFMBT1

References

PMID: 10661410 by Morel S., et al. Processing of some antigens by the standard proteasome but not by the immunoproteasome results in poor presentation by dendritic cells.

PMID: 17599839 by Wu S., et al. Human SFMBT is a transcriptional repressor protein that selectively binds the N-terminal tail of histone H3.