Endophilin-A3 Antibodies

AND SH3GL3 ELISA kits, Endophilin-A3 Proteins

Many biological assays use antibodies to detect Endophilin-A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endophilin-A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endophilin-A3 antibodies...

We validate the specificity of these antibodies to Endophilin-A3 by testing them on tissues known to express SH3GL3 positively and negatively. Browse below to find the SH3GL3 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SH3GL3 Infographic by Boster Bio

All SH3GL3 Products

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Specificity

Applications

Price

Anti-Endophilin-A3 SH3GL3 Antibody

Western blot analysis of various lysates, using SH3GL3 antibody at 1:1000 dilution

Human, Mouse, Rat

IHC, WB

$405
Cat # A09836
100ul

SH3GL3 (NM_003027) Human Recombinant Protein

Coomassie blue staining of purified SH3GL3 protein

$1062
Cat # PROTQ99963
20 µg

Anti-SH3GL3 Antibody (C-term)

Human

$299
Cat # M09836
80 µl

SH3GL3 (NM_003027) Human Over-expression Lysate

Human

$628
Cat # LS006457
20 µg, 100 µg

Anti-SH3GL3 Antibody Picoband®

Western blot analysis of SH3GL3 using anti-SH3GL3 antibody (A09836-1)

Flow Cytometry analysis of Jurkat cells using anti-SH3GL3 antibody (A09836-1)

Flow Cytometry analysis of U20S cells using anti-SH3GL3 antibody (A09836-1)

Human, Mouse, Rat

Flow Cytometry, WB

$370
Cat # A09836-1
100 μg/vial

SH3GL3 Overview

Facts about Endophilin-A3.

SH3GL3 3D structure. Source: alphafold

Endophilin-A3 (SH3GL3)

Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).

. .

Gene Information

Human
Gene Name:	SH3GL3
Uniprot:	Q99963
Entrez:	6457

Family

Belongs to:

endophilin family

Alternative Names

CNSA3; EEN-B2; endophilin-A3; SH3D2C; SH3-domain GRB2-like 3

Molecular Weight

Mass (kDA):
39.285 kDA

Genomic Context


Human

Location:	15q25.2
Sequence:	15; NC_000015.10 (83447123..83618743)

Tissue Specificity

Brain and testis.

Subcellular Localizations

Cytoplasm. Early endosome membrane; Peripheral membrane protein. Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons.

Diseases

Neoplasms
Huntington Disease
Malignant Neoplasms
Nervousness
Neoplasm Metastasis
Metastatic Malignant Neoplasm To The Lymph Node
Glioma
Oral Cavity Carcinoma
Neoplasm Invasiveness
Carcinoma
Mouth Neoplasms
Colorectal Cancer
Cell Invasion

Malignant Squamous Cell Neoplasm
Nephrotic Syndrome
Proteinuria Of Undiagnosed Cause
Nerve Degeneration
Glioblastoma
Malignant Paraganglionic Neoplasm
Tissue Adhesions

Interacting Proteins

ATXN2
HTT
RAPH1
SH3GL1
SH3GL2

Pathways

Cell Death
Endocytosis
Clathrin-mediated Endocytosis
Cell Adhesion
Methylation
Cell Migration
Dna Methylation
Vasculogenesis
Spermatid Differentiation

Rna Interference
Spermatogenesis
Glomerular Filtration

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SH3GL3

References

PMID: 9169142 by Giachino C., et al. A novel SH3-containing human gene family preferentially expressed in the central nervous system.

PMID: 9809064 by Sittler A., et al. SH3GL3 associates with the Huntingtin exon 1 protein and promotes the formation of polygln-containing protein aggregates.