Sedoheptulokinase Antibodies

AND SHPK ELISA kits, Sedoheptulokinase Proteins

Many biological assays use antibodies to detect Sedoheptulokinase, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Sedoheptulokinase in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Sedoheptulokinase antibodies...

We validate the specificity of these antibodies to Sedoheptulokinase by testing them on tissues known to express SHPK positively and negatively. Browse below to find the SHPK antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SHPK Infographic by Boster Bio

All SHPK Products

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Specificity

Applications

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Anti-CARKL (SHPK) Mouse Monoclonal Antibody [Clone ID: OTI3D7]

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SHPK (Right lane) cDNA for 48 hrs and lysed

Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-SHPK mouse monoclonal antibody

Anti-SHPK mouse monoclonal antibody (M09991-1) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SHPK

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M09991-1
100 µl

Anti-CARKL (SHPK) Mouse Monoclonal Antibody [Clone ID: OTI4E9]

HEK293T cells transfected with either SHPK (Myc-DDK-tagged) overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SHPK antibody (M09991)

Anti-SHPK mouse monoclonal antibody (M09991) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SHPK

Human, Mouse, Rat

Flow Cytometry, IF, WB

$523
Cat # M09991
100 µl

CARKL (SHPK) (NM_013276) Human Over-expression Lysate

Human

$628
Cat # LS023729
20 µg, 100 µg

SHPK Overview

Facts about Sedoheptulokinase.

SHPK 3D structure. Source: alphafold

Sedoheptulokinase (SHPK)

Acts as a modulator of macrophage activation through control of glucose metabolism. .

Gene Information

Human
Gene Name:	SHPK
Uniprot:	Q9UHJ6
Entrez:	23729

Family

Belongs to:

FGGY kinase family

Alternative Names

Carbohydrate kinase-like protein; carbohydrate kinase-like; CARKLEC 2.7.1.14; sedoheptulokinase; SHKFLJ32478

Molecular Weight

Mass (kDA):
51.491 kDA

Genomic Context


Human

Location:	17p13.2
Sequence:	17; NC_000017.11 (3608240..3636250, complement)

Tissue Specificity

Strongly expressed in liver, kidney and pancreas. Expressed at lower levels in placenta and heart. Very weakly expressed in lung and brain.

Subcellular Localizations

Cytoplasm.

Diseases

Cystinosis
Lysosomal Storage Diseases
Steroid Sulfatase Deficiency Disease
Storage Disease

Pathways

Transport
Macrophage Activation

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SHPK

References

PMID: 10673275 by Touchman J.W., et al. The genomic region encompassing the nephropathic cystinosis gene (CTNS): complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.

PMID: 18186520 by Wamelink M.M., et al. Sedoheptulokinase deficiency due to a 57-kb deletion in cystinosis patients causes urinary accumulation of sedoheptulose: elucidation of the CARKL gene.