Homeobox protein SIX1 Antibodies

AND SIX1 ELISA kits, Homeobox protein SIX1 Proteins

Many biological assays use antibodies to detect Homeobox protein SIX1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein SIX1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein SIX1 antibodies...

We validate the specificity of these antibodies to Homeobox protein SIX1 by testing them on tissues known to express SIX1 positively and negatively. Browse below to find the SIX1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for Homeobox protein SIX1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the SIX1 Western Blot Guide

SIX1 Infographic by Boster Bio

All SIX1 Products

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Product

Figures

Specificity

Applications

Price

Anti-SIX1 Antibody Picoband®

Western blot analysis of SIX1 using anti-SIX1 antibody (PB9889)

Human

$370
Cat # PB9889
100 μg/vial

SIX1 (NM_005982) Human Over-expression Lysate

Human

$628
Cat # LS006495
20 µg, 100 µg

Human SIX1 Recombinant Protein

3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain

SDS-PAGE, Denatured

$250
Cat # PROTQ15475
Starting from 20ug

SIX1 Overview

Facts about Homeobox protein SIX1.

SIX1 3D structure. Source: alphafold

Homeobox protein SIX1 (SIX1)

Transcription factor that's involved in the regulation of cell proliferation, apoptosis and embryonic development. Plays an important role in the development of many organs, including kidney, muscle and internal ear.

Based on context, functions as transcriptional repressor or activator. Lacks an activation domain, and requires interaction with EYA family members for transcription activation.

Gene Information

Human
Gene Name:	SIX1
Uniprot:	Q15475
Entrez:	6495

Family

Belongs to:

SIX/Sine oculis homeobox family

Alternative Names

BOS3; deafness, autosomal dominant 23; DFNA23; homeobox protein SIX1; sine oculis homeobox (Drosophila) homolog 1; sine oculis homeobox homolog 1 (Drosophila); Sine oculis homeobox homolog 1; SIX homeobox 1; TIP39

Molecular Weight

Mass (kDA):
32.21 kDA

Genomic Context


Human

Location:	14q23.1
Sequence:	14; NC_000014.9 (60643421..60649489, complement)

Tissue Specificity

Specifically expressed in skeletal muscle.

Subcellular Localizations

Nucleus. Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Branchio-oto-renal Syndrome
Neoplasm Metastasis
Carcinoma
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Mammary Neoplasms
Crest Syndrome
Glaucoma
Glaucoma, Open-angle
Complete Hearing Loss
Hypoplasia

Pituitary Diseases
Haploinsufficiency
Hypertrophy
Mammary Neoplasms, Experimental
Primary Open Angle Glaucoma
Rhabdomyosarcoma
Congenital Absence

Interacting Proteins

AES
EYA1
EYA2
MDFI

Pathways

Cell Proliferation
Neurogenesis
Eye Development
Regeneration
Cell Differentiation
Ear Development
Kidney Development
Organ Development
Pathogenesis
Inner Ear Development
Localization
Cell Death
Somitogenesis

Virulence
Cell Cycle
Delamination
Reverse Transcription
Cell Adhesion
Neural Tube Closure
Cell Migration

PTMs

Phosphorylation
Methylation
Demethylation

Cleavage
Acetylation
Dephosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SIX1

References

PMID: 8617500 by Boucher C.A., et al. Cloning of the human SIX1 gene and its assignment to chromosome 14.

PMID: 10801845 by Ford H.L., et al. Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein.