Homeobox protein SIX6 Antibodies

AND SIX6 ELISA kits, Homeobox protein SIX6 Proteins

Many biological assays use antibodies to detect Homeobox protein SIX6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein SIX6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein SIX6 antibodies...

We validate the specificity of these antibodies to Homeobox protein SIX6 by testing them on tissues known to express SIX6 positively and negatively. Browse below to find the SIX6 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SIX6 Infographic by Boster Bio

All SIX6 Products

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Product

Figures

Specificity

Applications

Price

Anti-Homeobox protein SIX6 Antibody Picoband®

7 Q&As

Western blot analysis of SIX6 using anti-SIX6 antibody (A06502-1)

Human

$370
Cat # A06502-1
100 μg/vial

SIX6 Colorimetric Cell-Based ELISA

Western blot analysis of extracts from HuvEc/COLO205 cells

Human, Mouse, Rat

ELISA

$480
Cat # EKC1661
1 kit, containing one 96-well plate and all necessary reagents

Human SIX6 Recombinant Protein

SDS-PAGE

$250
Cat # PROTO95475
Starting from 20ug

Homeobox protein SIX6 (SIX6) (NM_007374) Human Over-expression Lysate

Human

$628
Cat # LS004990
20 µg, 100 µg

SIX6 Overview

Facts about Homeobox protein SIX6.

SIX6 3D structure. Source: alphafold

Homeobox protein SIX6 (SIX6)

May be involved in eye development. .

Gene Information

Human
Gene Name:	SIX6
Uniprot:	O95475
Entrez:	4990

Family

Belongs to:

SIX/Sine oculis homeobox family

Alternative Names

homeobox protein SIX6; Homeodomain protein OPTX2; MCOPCT2; Optic homeobox 2; OPTX2; sine oculis homeobox (Drosophila) homolog 6; sine oculis homeobox homolog 6 (Drosophila); Sine oculis homeobox homolog 6; SIX homeobox 6; Six9

Molecular Weight

Mass (kDA):
27.687 kDA

Genomic Context


Human

Location:	14q23.1
Sequence:	14; NC_000014.9 (60509146..60512850)

Tissue Specificity

Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions.

Subcellular Localizations

Nucleus.

Diseases

Pituitary Diseases
Anophthalmos
Microphthalmos
Haploinsufficiency
Glaucoma
Cataract
Chromosomal Translocation
Glaucoma, Open-angle
Abnormal Degeneration
Congenital Ocular Coloboma (disorder)
Primary Open Angle Glaucoma
Branchio-oto-renal Syndrome

Dwarfism
Congenital Abnormality
Precursor T-cell Lymphoblastic Leukemia-lymphoma
Holoprosencephaly
Overlying Behavior
Hyperplasia
Polydactyly

Pathways

Eye Development
Cell Proliferation
Forebrain Development
Secretion
Cell Adhesion
Developmental Process
Brain Development
Neurogenesis
Cell Fate Determination
Pigmentation
Inner Ear Development
Virulence
Eye Morphogenesis

Circadian Behavior
Reverse Transcription
System Development
Translation
Cell Differentiation
Epithelium Development
Transdifferentiation

PTMs

Phosphoprotein

Research Areas

Vision

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SIX6

References

PMID: 10381575 by Lopez-Rios J., et al. Six9 (Optx2), a new member of the Six gene family of transcription factors, is expressed at early stages of vertebrate ocular and pituitary development.

PMID: 10512683 by Gallardo M.E., et al. Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies.