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- Table of Contents
Designing a Western blot for Homeobox protein SIX6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SIX6 Western Blot GuideFacts about Homeobox protein SIX6.
| Human | |
|---|---|
| Gene Name: | SIX6 |
| Uniprot: | O95475 |
| Entrez: | 4990 |

| Belongs to: |
|---|
| SIX/Sine oculis homeobox family |

homeobox protein SIX6; Homeodomain protein OPTX2; MCOPCT2; Optic homeobox 2; OPTX2; sine oculis homeobox (Drosophila) homolog 6; sine oculis homeobox homolog 6 (Drosophila); Sine oculis homeobox homolog 6; SIX homeobox 6; Six9
Mass (kDA):
27.687 kDA

| Human | |
|---|---|
| Location: | 14q23.1 |
| Sequence: | 14; NC_000014.9 (60509146..60512850) |
Expressed in the developing and adult retina. Also expressed in the hypothalamic and the pituitary regions.
Nucleus.





PMID: 10381575 by Lopez-Rios J., et al. Six9 (Optx2), a new member of the Six gene family of transcription factors, is expressed at early stages of vertebrate ocular and pituitary development.
PMID: 10512683 by Gallardo M.E., et al. Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies.