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- Table of Contents
SLC1A5 Antibodies
AND SLC1A5 ELISA kits, SLC1A5 Proteins
Many biological assays use antibodies to detect SLC1A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC1A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC1A5 antibodies...
Designing a Western blot for SLC1A5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SLC1A5 Western Blot GuideSLC1A5 Infographic by Boster Bio
All SLC1A5 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M01474
100 μg
Cat # M01474
100 μg
SLC1A5 Overview
Facts about Neutral amino acid transporter B(0).
Neutral amino acid transporter B(0) (SLC1A5)
Sodium-dependent amino acids transporter which has a wide substrate specificity, with a taste for zwitterionic amino acids. It accepts as substrates all neutral amino acids, such as glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids (PubMed:8702519, PubMed:29872227).
Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous mix of their plasma membranes, an essential process in placental development (PubMed:10708449, PubMed:23492904). .
Gene Information
| Human | |
|---|---|
| Gene Name: | SLC1A5 |
| Uniprot: | Q15758 |
| Entrez: | 6510 |
Family
| Belongs to: |
|---|
| dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family |
Alternative Names
AAAT; ASCT2M7VS1; ATB(0); Baboon M7 virus receptor; M7V1ATBO; neutral amino acid transporter B; neutral amino acid transporter B(0); R16; RD114 virus receptor; RD114/simian type D retrovirus receptor; RDR; RDRCFLJ31068; Sodium-dependent neutral amino acid transporter type 2; solute carrier family 1 (neutral amino acid transporter), member 5; Solute carrier family 1 member 5
Molecular Weight
Mass (kDA):
56.598 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 19q13.32 |
| Sequence: | 19; NC_000019.10 (46774883..46788594, complement) |
Tissue Specificity
Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Malignant Neoplasms
- Neoplasms
- Liver Carcinoma
- Hypoxia
- Liver Neoplasms
- Glioma
- Pre-eclampsia
- Choriocarcinoma
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Ischemia
- Malignant Paraganglionic Neoplasm
- Schizophrenia
Interacting Proteins
- RNF5
Pathways
- Transport
- Amino Acid Transport
- Glutamine Transport
- Localization
- Cell Growth
- Neutral Amino Acid Transport
- Pathogenesis
- Syncytium Formation
- D-serine Transport
- Glycine Transport
- Glycosylation
- Cell Death
- Autophagy
PTMs
- Phosphorylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC1A5
bosterbio.com/bosterbio-gene-info-cards/SLC1A5
References
PMID: 8702519 by Kekuda R., et al. Cloning of the sodium-dependent, broad-scope, neutral amino acid transporter Bo from a human placental choriocarcinoma cell line.
PMID: 10051606 by Rasko J.E.J., et al. The RD114/simian type D retrovirus receptor is a neutral amino acid transporter.